经纤维支气管镜肺泡灌洗治疗大叶性肺炎患儿的疗效研究  

Efficacy of Fiberoptic Bronchoscopic Alveolar Lavage in the Treatment Lobar Pneumonia in Children

作　　者：杨三珍[1] 陈炳强[1] 彭升[1] 何洲[1] YANG Sanzhen;CHEN Bingqiang;PENG Sheng;HE Zhou(Pediatric Internal Medicine Department,Gaozhou People's Hospital,Gaozhou 525200 Guangdong,China)

机构地区：[1]高州市人民医院小儿内科,广东高州525200

出　　处：《现代诊断与治疗》2023年第5期647-650,共4页Modern Diagnosis and Treatment

摘　　要：目的 分析经纤维支气管镜肺泡灌洗治疗大叶性肺炎患儿的临床疗效。方法 选取我院2020年7月至2022年7月收治的60例大叶性肺炎患儿,采用数字抽签法分为观察组和对照组各30例。观察组患儿采取纤维支气管镜肺泡灌洗联合常规治疗方案,对照组则采取常规治疗。对比两组患儿临床疗效、免疫相关指标测定水平和炎性因子、临床症状缓解时间和临床治疗时间。结果 治疗后,观察组免疫蛋白球M、免疫蛋白球A、免疫蛋白球G水平均明显低于对照组,差异有统计学意义(P<0.05);观察组的肺啰音消失、住院时间和咳嗽缓解及体温恢复时间均明显短于对照组,差异有统计学意义(P<0.05);观察组的治疗总有效率为93.34%,明显高于对照组的70%,差异有统计学意义(P<0.05);治疗后,观察组的C反应蛋白、肿瘤坏死因子-α和降钙素原测定水平均明显低于对照组,差异有统计学意义(P<0.05)。结论 针对大叶性肺炎患儿,临床可以结合其实际病况,在常规抗感染疗法基础上,为其增加纤维支气管镜肺泡灌洗治疗,该疗法有利于改善其临床症状,调节免疫和炎性水平,提升临床疗效。Objectives To analyze the clinical efficacy of fiberoptic bronchoscopic alveolar lavage in the treatment of lobar pneumonia in children.Methods A total of 60 children with lobar pneumonia admitted to our hospital from July 2020 to July 2022 were selected and divided into observation group and control group by digital lottery,with 30 cases in each group.The observation group was treated with fiberoptic bronchoscopic alveolar lavage combined with conventional treatment,while the control group received conventional treatment.The clinical efficacy,immune-related indicators and inflammatory factors,clinical symptom relief time and clinical treatment time were compared between the two groups.Results After treatment,the levels of Immunoglobulin M,Immunoglobulin A and Immunoglobulin G in the study group were significantly lower than those in the control group(P<0.05).The disappearance of lung rales,hospital stay,cough relief and body temperature recovery time in the observation group were significantly shorter than those in the control group(P<0.05).The total effective rate of treatment in the observation group was 93.34%,which was significantly higher than the 70%in the control group(P<0.05).The levels of C-reactive protein,tumor necrosis factor-αand procalcitonin in the observation group were significantly lower than those in the control group(P<0.05).Conclusions For children with lobar pneumonia,fiberoptic bronchoscopic alveolar lavage can be added on the basis of routine anti-infective therapy according to the actual condition,which may improve their clinical symptoms,regulate the immune and inflammatory levels,and improve clinical efficacy.

关 键 词：纤维支气管镜 肺泡灌洗 大叶性肺炎 临床疗效 

分 类 号：R725.6[医药卫生—儿科]