基于数据挖掘的中医药治疗支气管扩张症痰热壅肺证用药规律研究  

Study on Medication Law of TCM for the Treatment of Bronchiectasis with Phlegm-heat Obstructing Lung Syndrome Based on Data Mining

作　　者：朱小玲 张智琳 孔祥照 ZHU Xiaoling;ZHANG Zhilin;KONG Xiangzhao(Guangzhou University of Chinese Medicine,Guangzhou 510405,China;The Affiliated TCM Hospital of Guangzhou Medical University,Guangzhou 510130,China)

机构地区：[1]广州中医药大学,广东广州510405 [2]广州医科大学附属中医医院,广东广州510130

出　　处：《中国中医药图书情报杂志》2023年第4期90-94,共5页Chinese Journal of Library and Information Science for Traditional Chinese Medicine

基　　金：广东省中医药局项目(20212172);广州市中医药和中西医结合科技项目(20212A011007)。

摘　　要：目的探讨支气管扩张症痰热壅肺证的中医用药规律,为临床提供参考。方法计算机检索中国期刊全文数据库(CNKI)、中国学术期刊数据库(万方数据)、中文科技期刊数据库(VIP)建库至2022年10月20日收录的中医药治疗支气管扩张症痰热壅肺证研究文献。采用Excel2019软件统计用药频次、功效分类、性味归经,采用SPSS Modeler 18.0软件Apriori算法进行关联规则分析,采用SPSS Statistics 25.0软件对高频药物进行聚类分析,探究其组方规律。结果经筛选,纳入文献172篇,涉及172首处方、210味药物,总药物频次为2309次;高频药物有黄芩、甘草、桔梗、薏苡仁、鱼腥草等;药性以寒性、平性、温性为主,药味以甘味、苦味、辛味为主,主要归于肺经、胃经、脾经,药物多具清化热痰、止咳平喘等功效;聚类分析得到4类组方;常用药对有薏苡仁-桃仁、黄芩-桔梗、薏苡仁-冬瓜子、薏苡仁-芦根等。结论中医药治疗支气管扩张症痰热壅肺证用药以清化热痰和排脓为主,随证辅以健脾益气、燥湿化痰类药物。Objective To explore the medication law of TCM for the treatment of bronchiectasis with phlegmheat obstructing lung syndrome;To provide reference for clinical practice.Methods The literature about TCM for the treatment of bronchiectasis with phlegm-heat obstructing lung syndrome was retrieved from the China Journal Full-text Database(CNKI),China Academic Journals Database(Wanfang Data),and Chinese Science and Technology Journals Database(VIP)from the establishment of the databases to October 20,2022.Excel2019 software was used to count the frequency of medication,efficacy classification,property,taste and meridian tropism.SPSS Modeler 18.0 software Apriori algorithm was used for association rule analysis,and SPSS Statistics 25.0 software was used for clustering analysis of high-frequency drugs to explore the prescription law.Results After screening,172 articles were included,involving 172 prescriptions and 210 kinds of Chinese materia medica,and a total drug frequency of 2309 times.High-frequency drugs were Scutellariae Radix,Glycyrrhizae Radix et Rhizoma,Platycodonis Radix,Coicis Semen,Houttuynia Herba and etc.;the drug properties were mainly cold,mild,and warm,and the drug tastes were mainly sweet,bitter and pungent,which belonged to lung meridian,stomach meridian,and spleen meridian.Moat medicines had the efficacy of clearing phlegm-heat,and relieving cough and asthma;clustering analysis obtained 4 types of prescriptions;the commonly used medicinal pairs included Coicis Semen-Persicae Semen,Scutellariae Radix-Platycodonis Radix,Coicis Semen-Benincasae Semen,Coicis Semen-Phragmitis Rhizoma,etc.Conclusion TCM treatment for bronchiectasis with phlegm-heat obstructing lung syndrome is based on clearing phlegm-heat and draining pus,accompanied by methods such as strengthening the spleen and invigorating qi,drying and reducing phlegm.

关 键 词：支气管扩张症 痰热壅肺证 中药复方 数据挖掘 用药规律 

分 类 号：R2-03[医药卫生—中医学] R259.622.2