基于疾病或药物的儿童合理用药评价指标的构建方法  

Methods of developing evaluation indicators of rational drug use in children based on diseases or medicines

作　　者：陈哲 王其琼[1,2,3,4] 曾力楠 黄亮[1,2,3,4] 邹锟 李海龙[1,2,3,4] 贾知军 成果 张伶俐 CHEN Zhe;WANG Qiqiong;ZENG Linan;HUANG Liang;ZOU Kun;LI Hailong;JIA Zhijun;CHENG Guo;ZHANG Lingli(Department of Pharmacy,West China Second University Hospital,Sichuan University,Chengdu 610041,P.R.China;Evidence-Based Pharmacy Center,West China Second University Hospital,Sichuan University,Chengdu 610041,P.R.China;NMPA Key Laboratory for Technical Research on Drug Products in vitro and in vivo Correlation,Chengdu 610041,P.R.China;Key Laboratory of Birth Defects and Related Diseases of Women and Children,Sichuan University,Ministry of Education,Chengdu 610041,P.R.China;West China School of Pharmacy,Sichuan University,Chengdu 610041,P.R.China;Department of Pediatrics,West China Second University Hospital,Sichuan University,Chengdu 610041,P.R.China;Molecular Translational Medicine Laboratory,Translational Medicine Center of Sichuan University,Chengdu 610041,P.R.China)

机构地区：[1]四川大学华西第二医院药学部,成都610041 [2]四川大学华西第二医院循证药学中心,成都610041 [3]国家药品监督管理局药物制剂体内外相关性技术研究重点实验室,成都610041 [4]出生缺陷与相关妇儿疾病教育部重点实验室,成都610041 [5]四川大学华西药学院,成都610041 [6]四川大学华西第二医院儿科,成都610041 [7]四川大学转化医学中心分子转化医学实验室,成都610041

出　　处：《中国循证医学杂志》2023年第6期691-694,共4页Chinese Journal of Evidence-based Medicine

基　　金：四川省科技计划项目(编号:2020YFS0035)。

摘　　要：合理用药是全球广泛关注的重点问题。儿童作为药物使用的最高风险人群之一,其合理用药评价一直备受关注。本研究基于课题组前期研究结果,制定了针对儿童社区获得性肺炎、原发性肾病综合征、质子泵抑制剂等儿童合理用药评价指标并进行了实证研究,进一步总结和阐述基于疾病或药物的儿童合理用药评价指标的构建方法,为制定儿童合理用药评价指标提供方法学参考。Rational drug use is a global concern.As one of the highest risk groups for drug use,children's rational drug use has always been concerned.Based on the previous research results of the research group,we developed evaluation indicator systems for assessing rational drug use to treat community-acquired pneumonia and primary nephrotic syndrome in children and proton pump inhibitors in pediatric intensive care units and finished empirical research.This study further summarizes and expounds the construction ideas of rational drug use evaluation indicators for children based on diseases or drugs,and provides a reference for constructing children's rational drug use evaluation indicators.

关 键 词：儿童 合理用药 评价 指标 方法学 

分 类 号：R969.3[医药卫生—药理学]