Lighting up Oxytocin Neurons to Nurture the Brain  

作　　者：Fang Zhou Junqiang Zheng Han Xu 

机构地区：[1]Department of Neurobiology and Department of Neurology of the Second Affiliated Hospital,Zhejiang University School of Medicine,Hangzhou 310058,China [2]Liangzhu Laboratory,MOE Frontier Science Center for Brain Science and Brain-machine Integration,State Key Laboratory of Brain-machine Intelligence,Zhejiang University,Hangzhou 311121,China [3]NHC and CAMS Key Laboratory of Medical Neurobiology,Zhejiang University,Hangzhou 310058,China

出　　处：《Neuroscience Bulletin》2023年第5期866-868,共3页神经科学通报（英文版）

基　　金：supported by grants from the National Natural Science Foundation of China(32125018 and 32071005);the Fundamental Research Funds for the Central Universities,the MOE Frontiers Science Center for Brain Science&Brain-Machine Integration of Zhejiang University,and Innovative Research Team of High-level Local Universities in Shanghai(SHSMU-ZDCX20211102).

摘　　要：The sensory system develops earlier than the systems responsible for higher brain functions such as language and cognition[1].Moreover,sensory experiences in early life are critical for the development of the brain.However,how sensory experiences shape brain development is an important yet unresolved question in neuroscience.Previous work has demonstrated that deprivation of sensory inputs in the early developmental stage causes synaptic dysfunction in the sensory cortex.Interestingly,it has been reported that oxytocin can restore the deficits caused by somatosensory deprivation in neonatal mice,suggesting that oxytocin may play a key role in sensory-mediated synaptogenesis[2].Vision is one of the most important sensory inputs during early development in mammalians including humans[1],but the neural mechanism underlying vision-mediated brain development is still largely unknown.

关 键 词：NEONATAL neural SENSORY 

分 类 号：R338[医药卫生—人体生理学]