老年糖尿病合并胰腺癌的危险因素分析  

Analysis of the risk factors of pancreatic cancer in senile diabetes mellitus

作　　者：曾正洪 陈智 付前广 许静[4] ZENG Zheng-hong;CHEN Zhi;FU Qian-guang;XU Jing(Department of Endocrinology,Longquan Hospital,West China Hospital,Sichuan University,610100Chengdu,Sichuan,China;Department of Oncology,Longquan Hospital,West China Hospital,Sichuan University,610100Chengdu,Sichuan,China;Department of General Surgery,Longquan Hospital,West China Hospital,Sichuan University,610100Chengdu,Sichuan,China;Department of Endocrinology,West China Hospital,Sichuan University,Chengdu 610044,China)

机构地区：[1]四川大学华西医院龙泉医院内分泌科,四川成都610100 [2]四川大学华西医院龙泉医院肿瘤科,四川成都610100 [3]四川大学华西医院龙泉医院普通外科,四川成都610100 [4]四川大学华西医院内分泌科,四川成都610044

出　　处：《临床消化病杂志》2023年第3期177-180,共4页Chinese Journal of Clinical Gastroenterology

基　　金：2020年四川省卫生健康委员会科研课题(No:20PJ041)。

摘　　要：[目的]探讨老年糖尿病并发胰腺癌的相关因素。[方法]回顾性分析老年糖尿病并发胰腺癌患者100例(研究组)的临床资料,另选同期收治的老年糖尿病无并发胰腺癌患者100例作为对照组。分析老年糖尿病并发胰腺癌相关因素。[结果]经单因素分析计量资料结果表明,研究组与对照组性别、高血压、糖尿病病程、CEA、CA19-9、DBIL、TBIL、AST和ALT水平比较均差异无统计学意义(P>0.05);研究组患者体质指数>24、合并胆囊炎、合并慢性胰腺炎、有吸烟史均多于对照组,2组比较差异有统计学意义(P<0.05)。将上述单因素分析具有统计学差异的纳入Logistic多因素分析表明,体质指数>24、合并胆囊炎、合并慢性胰腺炎及吸烟史为影响并发胰腺癌危险因素。[结论]体质指数、胆囊炎、慢性胰腺炎和吸烟史为影响老年糖尿病并发胰腺癌的危险因素。[Objective]To explore the risk factors of pancreatic cancer in senile diabetes mellitus.[Methods]One hundred elderly patients with diabetes mellitus complicated with pancreatic cancer admitted to our hospital from June 2017to December 2021were selected as the study group,and 100elderly patients with diabetes mellitus without pancreatic cancer admitted to our hospital during the same period were selected as the control group.The risk factors for pancreases cancer in senile diabetes were analyzed.[Results]The results of single factor analysis showed that there was no statistical difference in the sex,hypertension and diabetes between the two groups(P>0.05).The body mass index>24in the study group was higher than that in the control group.Cholecystitis,chronic pancreatitis,smoking history was more than that in the control group(P<0.05).The results of single factor analysis showed that there was no significant difference in serum CEA,CA19-9,DBIL,TBIL,AST and ALT levels between the two groups(P>0.05).Logistic multivariate analysis showed that BMI>24,cholecystitis,chronic pancreatitis and smoking history were the risk factors for pancreatitis.[Conclusion]BMI,cholecystitis,chronic pancreatitis and smoking history are risk factors for elderly diabetes mellitus complicated with pancreatic cancer.

关 键 词：老年糖尿病 胰腺癌 相关因素 

分 类 号：R587.1[医药卫生—内分泌]