莪术油注射液化学成分、药理作用和临床应用的研究进展  

Research progress on chemical components,pharmacological effects and clinical application of Zedoary Turmeric Oil Injection

作　　者：孔红芳 袁书同 袁飞龙 姜程曦 KONG Hong-fang;YUAN Shu-tong;YUAN Fei-long;JIANG Cheng-xi(Department of Traditional Chinese Medicine,Xiangshan Hospital,Wenzhou Medical University,Xiangshan 315799,China;School of Pharmacy,Wenzhou Medical University,Wenzhou 325000,China;Hefei Future Drug Development Co.,Ltd.,Hefei 230036,China)

机构地区：[1]温州医科大学附属象山医院中医科,浙江象山315799 [2]温州医科大学药学院,浙江温州325000 [3]合肥市未来药物开发有限公司,安徽合肥230036

出　　处：《中草药》2023年第12期4053-4060,共8页Chinese Traditional and Herbal Drugs

基　　金：合肥未来药物开发有限公司横向课题(KJHX2016)。

摘　　要：莪术油注射液(Zedoary Turmeric Oil Injection,ZTOI)的主要成分是温莪术经水蒸气蒸馏提取的莪术油,其化学成分多为倍半萜类成分,具有抗病毒的功效。临床上广泛用于上呼吸道感染、消化道溃疡及病毒引起的肺炎、脑膜炎等。通过文献检索等方法,对ZTOI的化学成分、药理药效、临床应用和不良反应进行综述,为ZTOI的二次开发和临床应用提供理论依据。The main component of Zedoary Turmeric Oil Injection(莪术油注射液,ZTOI)is zedoary turmeric oil extracted by steam distillation from Wenyujin(Curcuma wenyujin).Its chemical composition is mostly sesquiterpene,which has antiviral effect.It is widely used in upper respiratory tract infection,digestive tract ulcer,viral pneumonia,meningitis,and so on.Through literature retrieval,this paper reviewed the research status of the chemical composition,pharmacological effect,clinical application,and adverse reactions of ZTOI in recent years,with view to providing theoretical basis for the secondary development and clinical application of ZTOI.

关 键 词：莪术油注射液 药理药效 临床应用 不良反应 Β-榄香烯 莪术二酮 莪术醇 

分 类 号：R285[医药卫生—中药学]