骨替代生物陶瓷材料的研究现状  

Research Status of Bioceramic Materials for Bone Substitute

作　　者：高金星 李丽亚 穆菁华 徐恩霞[1] 刘新红[1] 马成良[1] 张灿 张丽果 GAO Jinxing;LI Liya;MU Jinghua;XU Enxia;LIU Xinhong;MA Chengliang;ZHANG Can;ZHANG Liguo(School of Materials Science and Engineering,Zhengzhou University,Zhengzhou 450052,China;Henan Institute of Medical and Pharmaceutical Sciences,Zhengzhou University,Zhengzhou 450001,China)

机构地区：[1]郑州大学材料科学与工程学院,河南郑州450052 [2]郑州大学河南省医药科学研究院,河南郑州450001

出　　处：《郑州大学学报（工学版）》2023年第4期80-87,共8页Journal of Zhengzhou University（Engineering Science）

基　　金：国家自然科学基金资助项目(51872265);河南省科技攻关计划项目(222102240064);先进耐火材料国家重点实验室开放基金(SKLAR202108)。

摘　　要：针对骨替代生物材料的发展需求,简述了骨替代用高分子材料、金属材料、生物陶瓷材料和复合材料的发展现状,着重介绍了生物陶瓷材料作为骨替代材料在力学性能、化学性能和生物性能方面的优势。生物陶瓷材料因密度和成分与人骨相近、生物相容性显著、机械强度高、化学性质稳定等特点,在当今的骨替代材料领域中扮演着重要角色。对以磷酸盐、硅酸盐、氧化物和非氧化物为代表的生物陶瓷材料的研究现状进行了系统地探讨,并对生物陶瓷材料及其复合材料用于骨替代生物材料的优势和局限性进行讨论,最后对生物陶瓷材料未来的发展方向进行了展望。In view of the development demand of biomaterials for bone substitute,the development status of polymer materials,metal materials,bioceramic materials and composite materials for bone replacement were summarized.The advantages of bioceramic materials in mechanical properties,chemical properties and biological properties as bone substitute materials were emphatically introduced.The bioceramic materials play an important role in the field of bone substitute materials due to their similar density and composition to human bone,significant biocompatibility,high mechanical strength,and stable chemical properties.In this study,the research status of bioceramic materials represented by phosphate,silicate,oxides and non-oxides was systematically discussed,and the advantages and limitations of bioceramic materials and their composites as bone substitute biomaterials study were discussed.Finally,the future development direction of bioceramic materials was prospected.

关 键 词：骨替代材料 生物陶瓷材料 复合材料 生物性能 物化性能 

分 类 号：Q819[生物学—生物工程] TQ174[化学工程—陶瓷工业]