河池市金城江区健康成人促甲状腺激素正常参考值范围的建立  

Establishment of normal reference range of thyroid stimulating hormone for healthy adults in Jinchengjiang District of Hechi City

作　　者：吴坤 蒙恩绩 覃裕祺 任清清 韦姣 韦利飞 WU Kun;MENG En-ji;QIN Yu-qi(Department of Endocrinology,Hechi Traditional Chinese Medicine Hospital,Guangxi 547000,China)

机构地区：[1]河池市中医医院内分泌科,广西547000

出　　处：《中国临床新医学》2023年第6期620-623,共4页CHINESE JOURNAL OF NEW CLINICAL MEDICINE

基　　金：河池市科技计划项目(编号:河科AB193602)。

摘　　要：目的建立河池市金城江区健康成人促甲状腺激素(TSH)正常参考值范围。方法选择2015年1月至2022年8月于河池市中医医院进行健康体检的健康成人273名进行TSH检测,以第2.5百分位数至第97.5百分位数范围(P 2.5~P 97.5)确定正常参考值范围。结果河池市金城江区健康成人TSH正常参考值范围为0.48~4.26μIU/ml,与试剂盒厂家提供的正常参考值范围(0.4~4.5μIU/ml)相近,但范围更狭窄。男性TSH正常参考值范围为0.49~4.12μIU/ml;女性TSH正常参考值范围为0.47~4.09μIU/ml。男性和女性的TSH水平差异有统计学意义(Z=2.296,P=0.022)。TSH正常参考值范围与年龄的关联性不显著(P>0.05)。结论河池市金城江区健康成人TSH正常参考值范围可以作为区域性参考标准,有利于提高当地甲状腺疾病诊断的准确性。Objective To establish the normal reference range of thyroid stimulating hormone(TSH)for healthy adults in Jinchengjiang District of Hechi City.Methods Two hundred and seventy-three healthy adults who underwent physical examination in Hechi Traditional Chinese Medicine Hospital from January 2015 to August 2022 were selected,and TSH detection was performed on them.The range of normal reference values was determined in the 2.5 to 97.5 percentile range(P 2.5 to P 97.5).Results The normal reference range of TSH for healthy adults in Jinchengjiang District of Hechi City was(0.48-4.26)μIU/ml,which was similar to the normal reference range(0.4-4.5μIU/ml)provided by the kit manufacturer,but the range of the former was more narrow.The normal reference values of TSH for males ranged from 0.49 to 4.12μIU/ml,while the normal reference values of TSH for females ranged from 0.47 to 4.09μIU/ml.The difference in TSH levels was statistically significant between the males and the females(Z=2.296,P=0.022).There was no significant correlation between the normal reference range of TSH and age(P>0.05).Conclusion The normal reference range of TSH in healthy adults in Jinchengjiang District of Hechi City can be used as a regional reference standard for healthy adults in Hechi City,which is conducive to improving the accuracy of diagnosis for local thyroid diseases.

关 键 词：河池市 金城江区 健康成人 促甲状腺激素 正常参考值范围 

分 类 号：R58[医药卫生—内分泌]