Batch Preparation and Characterization of Electrospun Porous Polylactic Acid‑Based Nanofiber Membranes for Antibacterial Wound Dressing  

作　　者：Jing Yin Lan Xu Adnan Ahmed 

机构地区：[1]National Engineering Laboratory for Modern Silk,College of Textile and Clothing Engineering,Soochow University,Suzhou,China

出　　处：《Advanced Fiber Materials》2022年第4期832-844,共13页先进纤维材料（英文）

基　　金：The work is supported financially by National Natural Science Foundation of China(Grant no.11672198);Jiangsu Higher Education Institutions of China(Grant no.20KJA130001);Six Talent Peaks Project of Jiangsu Province(Grant no.GDZB-050);PAPD(A Project Funded by the Priority Academic Program Development of Jiangsu Higher Education Institutions).

摘　　要：A good wound dressing needs to promote wound healing and tissue repair when the skin is injured.In this study,a self-made spherical section free surface electrospinning device was used to produce large quantities of electrospun porous polylactic acid(PLA)/chitosan(CS)/aloin nanofiber membranes(NFMs)for antibacterial wound dressing.The porous structures of PLAbased nanofibers were controlled by adjusting the weight ratios of mixed solvent and solute.The results showed that highquality porous PLA/CS/aloin(PCA)NFMs were obtained when the weight ratios of chloroform/N,N-dimethylformamide and PLA:CS were 90/10 and 7:1,respectively.The porous PCA NFMs exhibited high porosity,acceptable mechanical properties,moderate hydrophobicity,good swelling property,and high water vapor transmission rate.Moreover,they also showed excellent blood coagulative,antibacterial,biocompatible properties,which had the potential to be used in the application of antibacterial wound dressings.

关 键 词：Batch preparation Polylactic acid/chitosan/aloin Nanofiber membranes Spherical section free surface electrospinning Antibacterial wound dressings 

分 类 号：TB383[一般工业技术—材料科学与工程]