定晕汤对肝阳上亢型后循环缺血患者的临床疗效和复发率的影响  

Effect of Dingyun Decoction on Clinical Efficacy and Recurrence Rate of Post-circulatory Ischemia Patients with Liver-yang Hyperactivity

作　　者：邢海辉 李巧云 陈丹 XING Haihui;LI Qiaoyun;CHEN Dan(Department of Neurology,Gaochun Hospital of Traditional Chinese Medicine,Nanjing,Jiangsu Province,211300 China;Department of Rehabilitation Medicine,Xuancheng People's Hospital,Xuancheng,Anhui Province,242000 China)

机构地区：[1]南京市高淳中医院神经内科,江苏南京211300 [2]宣城市人民医院康复医学科,安徽宣城242000

出　　处：《中外医疗》2023年第16期18-22,共5页China & Foreign Medical Treatment

基　　金：安徽省重点研究与开发计划项目(202104j07020008)。

摘　　要：目的评估定晕汤对肝阳上亢型的后循环缺血患者临床疗效观察和复发率的影响。方法便利选择2019年7月—2021年1月南京市高淳中医院收治的82例肝阳上亢型后循环缺血患者,随机分为对照组(n=41,口服盐酸氟桂利嗪胶囊)和观察组(n=41,口服盐酸氟桂利嗪胶囊联合定晕汤进行治)。对比两组临床疗效、眩晕症状控制情况、基底动脉血流情况、复发率。结果观察组治疗有效率为92.68%,显著高于对照组的73.17%,差异有统计学意义(χ^(2)=5.512,P<0.05);治疗后两组DHI评分、DARS评分均低于治疗前,且观察组低于对照组,差异有统计学意义(P<0.05);治疗后两组患者的基底动脉血流情况均较治疗前有明显增快,且观察组快于对照组,差异有统计学意义(P<0.05);治疗后24周随访,观察组复发率显著低于对照组,差异有统计学意义(P<0.05)。结论定晕汤治疗肝阳上亢型后循环缺血,可显著改善患者的基底动脉血流速度,从而有效控制其眩晕症状,显著提高患者的治疗效果,降低其复发率,应用价值较高。Objective To evaluate the effect of Dingyun decoction on clinical efficacy and recurrence rate of patients with hyperactive liver-yang posterior circulation ischemia.Methods 82 patients with post-circulation ischemia with liver-yang hyperactivity treated in Nanjing Gaochun Hospital of Traditional Chinese Medicine from July 2019 to January 2021 were conveniently selected and randomly divided into control group(n=41,oral flunarizine hydrochloride capsule)and observation group(n=41,oral Flunarizine hydrochloride capsule combined with Dingyun decoction).The clinical efficacy,vertigo symptom control,basilar artery flow and recurrence rate were compared between the two groups.Results The effective rate of the observation group was 92.68%,which was significantly higher than that of the control group(73.17%),and the difference was statistically significant(χ^(2)=5.512,P<0.05).DHI scores and DARS scores of the two groups after treatment were lower than before treatment,and the observation group was lower than control group,and the difference was statistically significant(P<0.05).After treatment,the basal artery blood flow in both groups increased significantly compared with that before treatment,and the observation group was faster than control group,and the difference was statistically significant(P<0.05).At 24 weeks follow-up after treatment,the recurrence rate of observation group was significantly lower than that of control group,and the difference was statistically significant(P<0.05).Conclusion Dingyun decoction can significantly improve the blood flow velocity of the basilar artery,effectively control the vertigo symptoms of the patients,significantly improve the therapeutic effect of the patients,reduce the recurrence rate,and have high application value.

关 键 词：定晕汤 肝阳上亢型 后循环缺血 临床疗效 复发率 

分 类 号：R4[医药卫生—临床医学]