不同病程演变的耐多药肺结核患者CT影像特征分析  

Analysis of CT imaging features of multi-drug resistance tuberculosis patients with different courses

作　　者：郭昌英 钟万 梅菊芳 GUO Changying;ZHONG Wan;MEI Jufang(Department of Imaging,Ganzhou,Ganzhou Fifth People's Hospital,Ganzhou,Jiangxi,341000,China)

机构地区：[1]赣州市第五人民医院影像科,江西赣州341000

出　　处：《当代医学》2022年第31期42-44,共3页Contemporary Medicine

基　　金：赣州市科学技术局(GZ2020ZSF295)。

摘　　要：目的分析不同病程演变的耐多药肺结核患者CT影像特征。方法选取2020年1月至2021年12月经药敏实验证实的35例单耐药肺结核(MR-TB)患者作为MR-TB组;另选取同期40例耐多药肺结核(MDR-TB)患者作为MDR-TB组。两组均实施CT检查,分析CT影像学表现。结果MDR-TB组消瘦、低热、盗汗、胸痛、乏力、间断性咯血临床症状发生率高于MR-TB组,差异有统计学意义(P<0.05);两组右肺、左肺病变位置发生率比较差异无统计学意义;两组单发空洞、多发空洞发生率比较差异无统计学意义;MDR-TB组病灶内钙化、肺毁损、胸膜钙化、脓/气胸、支气管扩张发生率均高于MR-TB组,差异有统计学意义(P<0.05)。结论不同病程演变的肺结核患者CT影像特征如存在钙化、肺部毁损、胸膜钙化、脓/气胸、支气管扩张即可高度怀疑MDR-TB。Objective To investigate the CT imaging features of multi-drug resistance tuberculosis patients with different course.Methods 35 patients with monodrug-resistant tuberculosis(MR-TB)confirmed by drug sensitivity test from January 2020 to December 2021 were retrospectively selected as MR-TB group,another 40 multi-drug resistance tuberculosis(MDR-TB)patients during the same periodwere selected as MDR-TB group.CT examination was performed in both groups,and CT imaging findings were analyzed.Results The incidence of clinical symptoms of thinness,low fever,sweating,chest pain,fatigue and intermittent hemoptysis in MDR-TB group was higher than that in MR-TB group,and the differences were statistically significant(P<0.05).There was no significant difference in the incidence of location of right and left pulmonary lesions between two groups.There was no significant difference in the incidence of single cavity and multiple cavity between the two groups.The incidence of intralesional calcification,lung damage,pleural calcification,pus/pneumothorax and bronchiectasis in MDR-TB group was higher than that in MR-TB group,and the difference was statistically significant(P<0.05).Conclusion The CT imaging features of tuberculosis patients with different course of disease evolution showed that MDR-TB could be highly suspected if there were calcification,pulmonary damage,pleural calcification,pus/pneumothorax and bronchiectasis.

关 键 词：单耐药 耐多药 肺结核 CT 影像学特征 

分 类 号：R521[医药卫生—内科学]