冠状动脉粥样硬化性心脏病患者经皮冠状动脉介入治疗术后预后不良情况及其危险因素分析  

Analysis of adverse prognosis and risk factors in patients with coronary heart disease after percutaneous coronary intervention

作　　者：王旭东[1] 马荟[1] 吴健[1] WANG Xudong;MAHui;WU Jian(Department of Cardiology,Anshan Hospital,The First Affiliated Hospital of China Medical University,Anshan,Liaoning,114000,China)

机构地区：[1]中国医科大学附属第一医院鞍山医院心内科,辽宁鞍山114000

出　　处：《当代医学》2022年第30期126-129,共4页Contemporary Medicine

摘　　要：目的分析冠状动脉粥样硬化性心脏病患者经皮冠状动脉介入治疗(PCI)术后预后不良情况及其危险因素。方法回顾性分析2019年1月至2021年12月本院收治的158例冠状动脉粥样硬化性心脏病PCI术后患者的临床资料,根据30 d内是否发生主要心血管不良事件(MACE)分为预后良好患者(n=124)和预后不良患者(n=34)。比较患者临床资料,计算术后30 d内MACE发生率,分析PCI术后预后不良的危险因素。结果冠状动脉粥样硬化性心脏病患者PCI预后不良发生率为21.52%。多因素Logistic分析结果显示,年龄≥60岁、合并高脂血症、病变支数≥2条、未应用替罗非班、发病至PCI时间≥3 h为冠状动脉粥样硬化性心脏病患者PCI术后预后不良的危险因素(P<0.05)。结论冠状动脉粥样硬化性心脏病患者PCI术后预后不良与年龄≥60岁、合并高脂血症、病变支数≥2条、未应用替罗非班、发病至PCI时间长等因素密切相关,临床可根据以上指标给予针对性治疗,进而改善患者预后。Objective To analyze the poor prognosis and risk factors of percutaneous coronary intervention(PCI)in patients with coronary heart disease.Methods The clinical data of 158 patients with PCI with coronary heart disease admitted to our hospital from January 2019 to December 2021 were retrospectively analyzed,and they were divided into patients with good prognosis(n=124)and patients with poor prognosis(n=34)according to whether major adverse cardiovascular events(MACE)occurred within 30 d.The clinical data of patients were compared,the incidence of MACE within 30 d after surgery was calculated,and the risk factors for poor prognosis after PCI were analyzed.Results The incidence of poor PCI in patients with coronary heart disease was 21.52%.The results of multivariate logistic analysis showed that age≥60 years,hyperlipidemia,≥2 number of lesions,tirofiban was not used,and from onset to PCI≥3 h were risk factors for poor prognosis after PCI in patients with coronary heart disease(P<0.05).Conclusion The poor prognosis of PCI in patients with coronary heart disease is closely related to the factors such as age≥60 years,hyperlipidemia,≥2 number of lesions,tirofiban not applied,and long time from onset to PCI.

关 键 词：冠状动脉粥样硬化性心脏病 经皮冠状动脉介入治疗 不良心血管事件 替罗非班 

分 类 号：R541.4[医药卫生—心血管疾病]