艾滋病患儿照顾者的特征及其对患儿抗病毒治疗服药依从性的影响  

Characteristics of caregivers of children with acquired immune deficiency and their impact on antiretroviral medication adherence in children

作　　者：傅得佳 林菁 朱炜春 柯迎春[2] 杨华彬 FU Dejia;LIN Jing;ZHUWeichun;KE Yingchun;YANG Huabin(Department of Pediatrics,No.8 Affiliated Hospital of Guangzhou Medical University,Guangzhou,Guangdong,510080,China;Department of Pediatric Nephrology,GuangzhouWomen and Children's Medical Center,Guangzhou,Guangdong,510623,China;不详)

机构地区：[1]广州医科大学附属市八医院儿科,广东广州510080 [2]广州医科大学附属市八医院感染病中心,广东广州510080 [3]广州市妇女儿童医疗中心小儿肾内科,广东广州510623

出　　处：《当代医学》2022年第32期71-74,共4页Contemporary Medicine

基　　金：广州市卫生健康科技项目(20201A010022)。

摘　　要：目的探讨艾滋病(AIDS)患儿照顾者的特征及其对患儿抗病毒治疗服药依从性的影响。方法选取2020年5月至2021年4月本院收治的60例艾滋病患儿作为研究对象,采用结构式访谈方法对儿童及家长或监护人进行一对一、面对面深入访谈后收集相关资料。分析儿童AIDS患者抗病毒治疗效果及抗病毒药物对患儿生长发育的影响。结果单因素分析结果显示,照顾者身份为父母(包括单亲或双亲)的患儿服药依从性(36.67%)高于隔代或其他亲属患儿(11.67%),差异有统计学意义(P<0.05);认知程度高的服药依从性(30.00%)高于认知程度差的服药依从性(16.67%),差异有统计学意义(P<0.05);担心服药风险的依从性(10.00%)和不担心服药风险服药依从性(45.00%)比较差异无统计学意义;有告知意愿的依从性(25.00%)和无告知意愿的依从性(30.00%)差异无统计意义。采用多因素Logistic回归分析结果显示,照顾者为父母,对AIDS认知程度好为服药依从性的保护因素(P<0.05)。结论艾滋病患儿照顾者对患儿抗病毒治疗服药依从性影响因素,与照顾者身份(如隔代或非直属亲属)及其对服药依从性认知程度有明显相关性,患儿的服药依从性要高于隔代或其他亲属患儿的服药依从性。Objective To investigate the characteristics of caregivers of children with AIDS and its effect on antiretroviral medication compliance.Methods Atotal of 60 children with AIDS admitted to our hospital from May 2020 to April 2021 were selected as the research subjects,and the structured interview method was used to collect relevant data after one-on-one and face-to-face in-depth interviews with children,parents or guardians.The effect of antiviral therapy and the effect of antiviral drugs on the growth and development of children with AIDS were analyzed.Results The results of univariate analysis showed that the medication compliance(36.67%)of children with caregiver status as parents(including single or both parents)was higher than that of children with intergenerational or other relatives(11.67%),with a statistically significant difference(P<0.05),medication compliance with high cognitive degree(30.00%)was higher than that with poor cognitive degree(16.67%),with a statistically significant difference(P<0.05),there was no significant difference between medication compliance(10.00%)and medication compliance(45.00%)who were not worried about taking risks.There was no significant difference between the adherence with informed intention(25.00%)and the adherence with no informed intention(30.00%).The results of multivariate Logistic regression analysis showed that the caregiver was the parent,and the good awareness ofAIDS was the protective factor of medication compliance(P<0.05).Conclusion The factors influencing the adherence of caregivers of children with AIDS on antiretroviral therapy are significantly correlated with the identity of caregivers(such as generational or non-immediate relatives)and their awareness of medication compliance,and the medication compliance of children is higher than that of children with intergenerational or other relatives.

关 键 词：艾滋病患儿照顾者 特征 抗病毒 服药依从性 影响 

分 类 号：R512.91[医药卫生—内科学]