基于CiteSpace干细胞神经元修复的可视化分析  

Visual Analysis of Stem Cells Neuron Repair Based on CiteSpace

作　　者：黄思颖 郭铭娜 邹倩倩 郑琳乐 陈婷婷 刘松松 龚浩 HUANG Si-ying;GUO Ming-na;ZOU Qian-qian;ZHENG Lin-le;CHEN Ting-ting;LIU Song-song;GONG Hao(School of Life Sciences,Huizhou University,Huizhou 516007,Guangdong,China)

机构地区：[1]惠州学院生命科学学院,广东惠州516007

出　　处：《医学信息》2023年第13期24-30,共7页Journal of Medical Information

基　　金：广东省本科高校教学质量与教学改革工程建设项目(编号:粤教高函〔2020〕19号);广东省基础与应用基础研究基金项目(编号:2019A1515110470)。

摘　　要：目的总结国内外对干细胞神经元修复的研究现状及发展趋势,为后续该领域的研究提供参考。方法以Web of Science数据库中主题词为stem cell neural repair*,时间范围为2012-2021年的2729篇文献为研究对象,运用CiteSpace软件,通过文献计量法对干细胞神经元修复研究的发文量年代分布、关键词突现等进行可视化分析。结果文献发文量的年度分布主要呈现4个阶段,总体呈上升趋势;亚洲、美州和欧洲的作者发表论文的数量居多,其中亚洲以我国为代表发文量有1070篇,占论文发文量的34.30%;干细胞神经元修复的高频关键词为“neural stem cell”“stem cell”等;聚类网络共形成axonal regeneration、Parkinsons disease等22个聚类;“central nervous system”的突现强度最大;轴突再生、帕金森病、细胞分化等领域的研究时间较长;文献共被引中引用最多的文献是“Cell transplantation therapy for spinal cord injury”,共被引频次为57次。结论干细胞神经元修复的相关研究总体处于上升趋势,我国、美国、英国、加拿大是该研究的主力军,学者们在疾病领域、保健衰老、美容养颜方面对干细胞神经元修复均开展了研究,主要集中在疾病、治疗方法、分子机制研究领域及相关细胞4个领域,共被引文献的研究主要围绕脊髓损伤、细胞治疗、神经再生等方面。Objective To summarize the research status and development trend of stem cell neuron repair at home and abroad,and to provide reference for subsequent research in this field.Methods The 2729 papers in the Web of Science database with the subject term of stem cell neural repair*and the time range of 2012 to 2021 were taken as the research object.CiteSpace software was used to visually analyze the distribution of publication years and keyword emergence of stem cell neural repair research by bibliometric method.Results The annual distribution of the number of papers published in the literature mainly presents four stages,with an overall upward trend;the number of papers published in Asia,the Americas and Europe is the largest.Among them,there were 1070 papers published in Asia represented by China,accounting for 34.30%of the papers published.High frequency keywords for stem cell neuron repair were"neural stem cell""stem cell",etc.A total of 22 clusters were formed in the clustering network,such as axonal regeneration,Parkinsons disease and so on.The emergence intensity of"central nervous system"was the highest.Studies in the fields of axonal regeneration,Parkinsons disease,and cell differentiation had taken a long time.The most cited literature was"Cell transplantation therapy for spinal cord injury",with a total citation frequency of 57 times.Conclusion Research related to stem cell neuronal repair is generally on the rise,with China,the United States,the United Kingdom,and Canada being the mainstays of this research.Scholars have conducted research on stem cell neuronal repair in the areas of disease,health care aging,and beauty care,mainly focusing on four areas of disease,therapeutic approaches,molecular mechanism research areas,and related cells,with studies in the total cited literature mainly centering on spinal cord injury,cell therapy,and nerve regeneration.

关 键 词：神经元 干细胞修复 文献计量法 CITESPACE 可视化分析 

分 类 号：R651[医药卫生—外科学]