回收式自体输血在产后出血产妇中的应用效果及对红细胞流变学的影响  

Application effect of salvaged autotransfusion on parturients with postpartum hemorrhage and its influences on red cell rheology

作　　者：谭晓勇 吴斌斌[1] TAN Xiaoyong;WU Binbin(Surgical Anesthesiology Department,Hanzhong Central Hospital,Hanzhong 723000,China)

机构地区：[1]陕西省汉中市中心医院手术麻醉科,陕西汉中723000

出　　处：《临床医学研究与实践》2023年第19期88-91,共4页Clinical Research and Practice

摘　　要：目的探讨回收式自体输血在产后出血产妇中的应用效果。方法选择2017年8月至2020年12月在本院进行诊治的64例产后出血产妇作为研究对象,根据入院顺序将其分为异体组与回收组,各32例。异体组给予常规同种异体输血治疗,回收组给予回收式自体输血治疗。比较两组的治疗效果。结果两组的子宫切除率、住院时间比较,差异无统计学意义(P>0.05)。术前、术后24 h,两组的血红蛋白(Hb)水平、血细胞比容(HCT)、血小板计数(PLT)比较,差异无统计学意义(P>0.05)。回收组的不良反应总发生率为9.38%,低于异体组的37.50%,差异具有统计学意义(P<0.05)。输血后7 d,两组的全血黏度、血浆黏度均低于输血前,且回收组低于异体组,差异具有统计学意义(P<0.05);输血前、输血后7 d,两组的红细胞聚集指数、红细胞变形指数比较,差异无统计学意义(P>0.05)。结论回收式自体输血应用于产后出血产妇中并不会影响其治疗进程及红细胞流变学,且能减少输血不良反应的发生,改善产妇的全血黏度、血浆黏度,值得推广应用。Objective To explore the effect of salvaged autotransfusion of parturients with postpartum hemorrhage.Methods A total of 64 parturients with postpartum hemorrhage treated in our hospital from August 2017 to December 2020 were selected as the research objects.According to the order of admission,the parturients were divided into allograft group and recovery group,with 32 cases in each group.The allograft group was treated with routine allogeneic blood transfusion,while the recovery group was treated with salvaged autotransfusion.The therapeutic effects of the two groups were compared.Results There were no significant differences in hysterectomy rate and hospitalization time between the two groups(P>0.05).There were no significant differences in hemoglobin(Hb)level,hematocrit(HCT)and platelet count(PLT)between the two groups before and 24 h after surgery(P>0.05).The total incidence of adverse reactions in the recovery group was 9.38%,which was lower than 37.50%in the allograft group,and the difference was statistically significant(P<0.05).At 7 d after transfusion,the whole blood viscosity and plasma viscosity in both groups were lower than those before transfusion,those in the recovery group were lower than the allograft group,and the differences were statistically significant(P<0.05);there were no significant differences in erythrocyte aggregation index and erythrocyte deformation index between the two groups before and 7 d after transfusion(P>0.05).Conclusion The salvaged autotransfusion applied in parturients with postpartum hemorrhage does not affect the course of treatment and red cell rheology,and can reduce the occurrence of adverse transfusion reactions,improve the whole blood viscosity and plasma viscosity,which is worthy of popularization and application.

关 键 词：回收式自体输血 产后出血 红细胞流变学 输血不良反应 

分 类 号：R457.1[医药卫生—治疗学]