Fructans from Agave enhance probiotic yoghurt by modulating gut microbiota on children with overweight or obesity  

作　　者：Marco U.Martinez-Martinez Daniel V´azquez-Maldonado Stefan Ratering Cesar Godínez-Hern´andez Rosa Isela Ortiz-Basurto Ruth ESoria-Guerra Bellinda Schneider Bertha I.Ju´arez-Flores Diana P.Portales-P´erez Sylvia Schnell Fidel Martinez-Gutierrez 

机构地区：[1]Posgrado en Ciencias Farmacobiologicas,Universidad Autonoma de San Luis Potosi,Mexico [2]Institute of Applied Microbiology Justus Liebig University Giessen,Germany(3)Instituto de Zonas Deserticas Universidad Autonoma de San Luis Potosi,Mexico [3]Instituto de Investigaci´on de Zonas Des´erticas,Universidad Aut´onoma de San Luis Potosí,Mexico [4]Laboratorio Integral de Investigaci´on en Alimentos,Tecnol´ogico Nacional de Mexico/Instituto Tecnol´ogico de Tepic,Nayarit,Mexico [5]Centro de Investigaci´on en Ciencias de la Salud y Biomedicina,Universidad Aut´onoma de San Luis Potosí,Mexico

出　　处：《Food Bioscience》2022年第2期164-172,共9页食品生物科学（英文）

基　　金：Thanks to Professor Celia Aradillas for the entailment with the education authorities of the full-time school program,as well as,to the company Yakult S.A.de C.V.,for providing the dairy products used in research.

摘　　要：Overweight and obesity in children are an increasing public health problem,and the influence the gut microbiota has on it,is still discussed.The consumption of prebiotics has been studied in children with overweight and obesity after an intervention with fermented milk,supplemented with different fructans like prebiotics,was carried out to obtain a healthy microbiota.Children were randomly assigned into three groups,a double-blind intervention was carried out,receiving different fermented milk products for 6 weeks,including the following supplements:Lactobacillus casei strain Shirota,L.casei strain Shirota with inulin or L.casei strain Shirota with fructans from Agave salmiana Otto ex Salm-Dyck.DNA was extracted from stool samples and the differential abundance of ASV was monitored by high throughput 16S rRNA gene sequencing.A synbiotic with fructans from A.salmiana stimulated the abundance and diversity of the microbiota,specifically on genera Faecalibacterium and Holdemanella,thus,leading to a healthier gut microbiota,which led to obtaining the best anthropometric changes in synbiotic groups.Synbiotic intervention may provide health benefits to children with overweight or obesity by increasing the richness of the gut microbiota and stimulate beneficial bacteria.Nevertheless,more studies are needed to get a better understanding of the mechanisms of action.

关 键 词：Beta diversity Gut microbiota Mexico Prebiotic Probiotic 

分 类 号：TS201.3[轻工技术与工程—食品科学]