The water-soluble bicyclic 2-pyridone-based fluorescent probe for fast and selective detection of hypochlorite  

作　　者：Qian Zhou Shanqiang Wang Xiaoyun Ran Linzhi Shen Xiaolin Luo Gui Wang Hui Yang Zhouyu Wang Xiaoqi Yu 

机构地区：[1]Asymmetric Synthesis and Chiral Technology Key Laboratory of Sichuan Province,Research and Application of Small Organic Chiral Molecules Key Laboratory of Yibin City,Department of Chemistry,Xihua University,Chengdu 610039,China [2]School of Food and Bioengineering,Xihua University,Chengdu 610039,China [3]Key Laboratory of Green Chemistry and Technology,Ministry of Education,College of Chemistry,Sichuan University,Chengdu 610064,China

出　　处：《Chinese Chemical Letters》2023年第6期432-436,共5页中国化学快报（英文版）

基　　金：financially supported by the National Natural Science Foundation of China(No.21877082);the International Science and Technology Innovation Cooperation Project of Sichuan Province(No.2021YFH0132);the Sichuan Science and Technology Program(No.2021YFG0291);the Undergraduate Scientific and Technological Innovation Project(Nos.2021127,2021130),Xihua University。

摘　　要：As a strong oxidizer,hypochlorite(Cl O^(-))are widely employed as bleaching agents and disinfectants.Determination of ClO^(-)is required to ensure bactericidal effects and avoid hazards caused by excessive residual chlorine.Herein,the derivative bicyclic 2-pyridone,namely DHIP-Py,was prepared successfully to establish a new ClO^(-)-quantitative method.The probe exhibits excellent Cl O^(-)selectivity over other ROS and anions/cations,high sensitivity(LOD=1.32μmol/L),fast response(<5 s),and wide-p H tolerance(pH4~10).Benefit from its good water solubility,DHIP-Py is well suited for water sample analysis and has been successfully applied to detect Cl O^(-)in real-world food and environmental samples,including tap water,bottled water and river water.The detection results were essentially identical to that of obtained from traditional DPD method.Moreover,visual detection of Cl O^(-)via filter paper-based solid sensor and imaging of ClO^(-)in Escherichia coli were also achieved by DHIP-Py.These satisfactory results demonstrate that this bicyclic 2-pyridone-based hypochlorite probe is a promising free chlorine chemosensor with great potential for analytical applications.

关 键 词：Fluorescent probe HYPOCHLORITE Bicyclic 2-pyridone Tap water BIOIMAGING 

分 类 号：O657.3[理学—分析化学] TP212[理学—化学]