儿童原发性肾病综合征糖皮质激素性眼损害的相关研究  

Study on glucocorticoid-induced eye damage in children with primary nephrotic syndrome

作　　者：潘瑞英 PAN Ruiying(Pediatric Department of 924 th Hospital of the PLA Joint Logistics Support Force,Guilin 541002,China)

机构地区：[1]中国人民解放军联勤保障部队第九二四医院儿科,广西桂林541002

出　　处：《中国中西医结合儿科学》2023年第3期203-207,共5页Chinese Pediatrics of Integrated Traditional and Western Medicine

基　　金：广西壮族自治区卫生健康委员会自筹经费科研项目(Z20210436)。

摘　　要：原发性肾病综合征是儿童最常见的肾小球疾病之一。长期口服糖皮质激素是原发性肾病综合征公认的一线治疗方案。由于长期使用糖皮质激素会导致高眼压、青光眼、白内障等眼部损害。本文将对原发性肾病综合征糖皮质激素性眼损害的流行病学、风险因素、发病机制、诊断及临床表现、临床管理和治疗进行综述。建立原发性肾病综合征患儿长期糖皮质激素治疗过程中眼损害的早筛查、早诊断、早治疗,有效保证儿童眼健康。Primary nephrotic syndrome(PNS)is one of the most common glomerular diseases in children.Long-term oral glucocorticoids are recognized as the first-line treatment for PNS.Long-term use of glucocorticoids can lead to eye damage such as high eye pressure,glaucoma and cataracts.This article reviews the epidemiology,risk factors,pathogenesis,diagnosis,clinical manifestations,clinical management and treatment of glucocorticoid-induced eye damage in PNS.By establishing early screening,early diagnosis and early treatment of eye damage in PNS children during long-term glucocorticoid therapy,we hope to effectively ensure children′s eye health.

关 键 词：原发性肾病综合征 糖皮质激素 眼损害 儿童 

分 类 号：R725.9[医药卫生—儿科]