神经肌肉电刺激联合呼吸训练对慢性阻塞性肺疾病合并肌少症患者肺功能及运动耐力的影响  

Effects of neuromuscular electrical stimulation combined with respiratory training on pulmonary function and exercise tolerance in patients with chronic obstructive pulmonary disease complicated with myopenia

作　　者：曹梅[1] 马晶[2] 肖江琴[3] Cao Mei;Ma Jing;Xiao Jiangqin(Department of Traditional Chinese Medicine,People's Hospital of Xinjiang Uygur Autonomous Region,Urumqi 830000,China)

机构地区：[1]新疆维吾尔自治区人民医院中医科,乌鲁木齐830000 [2]新疆维吾尔自治区人民医院急救中心,乌鲁木齐830000 [3]新疆维吾尔自治区人民医院内科,乌鲁木齐830000

出　　处：《中华保健医学杂志》2023年第3期257-260,共4页Chinese Journal of Health Care and Medicine

基　　金：新疆维吾尔自治区自然科学基金资助项目(2022D01C111)。

摘　　要：目的探讨神经肌肉电刺激(neuromuscular electrical stimulation,NMES)联合呼吸训练对慢性阻塞性肺疾病(chronic obstructive pulmonary disease,COPD)合并肌少症患者肺功能及运动耐力的影响。方法选取2020年6月~2022年5月新疆维吾尔自治区人民医院收治的COPD稳定期合并肌少症患者196例,抽签随机分为观察组和对照组,每组各98例。两组均进行常规干预,对照组进行呼吸训练干预,观察组在对照基础上联合NMES干预。比较两组干预前后肺功能指标[1秒用力呼气容积占预计值百分比(FEV1%Pred)、用力肺活量占预计值百分比(FVC%Pred)、FEV1/FVC]水平;比较两组干预前后COPD评估测试量表(CAT)、圣乔治呼吸问卷(SGRQ)评分;比较两组干预前后6 min步行试验(6MWT)和骨骼肌质量指数(ASMI);比较两组干预前后医院焦虑抑郁量表(HADS)、日常生活能力量表(ADL)评分。结果干预前两组FEV1%Pred、FVC%Pred、FEV1/FVC水平比较,差异无统计学意义(P>0.05);干预后两组FEV1%Pre、FVC%Pre、FEV1/FVC水平均高于同组干预前,差异有统计学意义(P<0.05),但组间比较差异无统计学意义(P>0.05)。干预后,两组CAT评分、SGRQ评分均低于同组干预前,且观察组低于对照组,差异有统计学意义(P<0.05)。干预后,两组6MWT和ASMI指数均高于同组干预前,且观察组高于对照组,差异有统计学意义(P<0.05)。干预后,两组HADS评分低于同组干预前,ADL评分高于同组干预前,差异有统计学意义(P<0.05);观察组干预后HADS评分低于对照组干预后,ADL评分高于对照组干预后,差异有统计学意义(P<0.05)。结论NMES联合呼吸训练用于COPD合并肌少症,可显著改善患者呼吸困难症状,提高运动耐力及生活质量。Objective To investigate the effects of neuromuscular electrical stimulation(NMES)combined with respiratory training on pulmonary function and exercise tolerance in patients with chronic obstructive pulmonary disease(COPD)and myopenia.Method A total of 196 patients with stable COPD and myopenia,admitted to our hospital from June 2020 to May 2022,were randomly assigned to either the observation group or the control group,with 98 patients in each group.Both groups received routine intervention,while the control group received respiratory training intervention and the observation group received NMES intervention in additional to the control measures.The levels of pulmonary function indexes(FEV1%Pred,FVC%Pred,FEV1/FVC)before and after intervention were compared between the two groups.The scores of COPD assessment test(CAT)and St.George's respiratory questionnaire(SGRQ)before and after intervene were also compared.Additonally,the six-minute walk test(6MWT)and skeletal muscle mass index(ASMI)were assessed before and after the intervention;The scores of HADS and ADL were compared between the two groups before and after the intervention.Results There was no significant difference in FEV1%Pred,FVC%Pred and FEV1/FVC levels between the two groups before and after intervention(P>0.05).The levels of these pulmonary function indexes significantly improved after the intervention within each group(P<0.05).The CAT score and SGRQ score in both groups after intervene were lower than those of the same group before intervene(P<0.05);The CAT score and SGRQ score of the observation group after intervene were lower than those of the control group after intervene(P<0.05).After the intervention,the 6MWT and ASMI indexes significantly increased for both groups(P<0.05);The 6MWT and ASMI indexes in the observation group were higher than those in the control group after intervene(P<0.05).The HADS score decreased and the ADL score increased for both groups after the intervention(P<0.05);The HADS score of the observation group was lower than th

关 键 词：神经肌肉电刺激 呼吸训练 慢性阻塞性肺疾病 肌少症 肺功能 运动耐力 

分 类 号：R563[医药卫生—呼吸系统]