光子治疗仪联合藻酸盐粉在痔病术后创面愈合中的应用效果  

Effect of photon therapy apparatus combined with alginate powder on wound healing after hemorrhoidal surgery

作　　者：丁伟伟 刘巧 徐红 许敏 尚超 陈贤 DING Weiwei;LIU Qiao;XU Hong;XU Min;SHANG Chao;CHEN Xian(Department of Wound Stoma Clinic,Jiangning Hospital Affiliated to Nanjing Medical University,Jiangsu Province,Nanjing 210000,China;Department of Nursing,Jiangning Hospital Affiliated to Nanjing Medical University,Jiangsu Province,Nanjing 210000,China;Department of Anorectal,Jiangning Hospital Affiliated to Nanjing Medical University,Jiangsu Province,Nanjing 210000,China;Department of Outpatient,Jiangning Hospital Affiliated to Nanjing Medical University,Jiangsu Province,Nanjing 210000,China)

机构地区：[1]南京医科大学附属江宁医院伤口造口门诊,江苏南京210000 [2]南京医科大学附属江宁医院护理部,江苏南京210000 [3]南京医科大学附属江宁医院肛肠科,江苏南京210000 [4]南京医科大学附属江宁医院门诊,江苏南京210000

出　　处：《中国医药导报》2023年第16期107-110,共4页China Medical Herald

基　　金：江苏省南京市卫生科技发展专项资金项目(YKK19132)。

摘　　要：目的探讨光子治疗仪联合藻酸盐粉对痔病术后创面愈合的效果。方法选取2020年2月至9月南京医科大学附属江宁医院进行手术治疗的痔病患者80例为研究对象,根据随机数字表法将其分为对照组和研究组,每组40例。对照组采用光子治疗仪治疗,研究组采用光子治疗仪联合藻酸盐粉治疗。比较两组临床疗效;比较两组伤口好转时间、肛门水肿消失时间、出血消失时间、渗液消失时间;比较两组治疗前后的炎症指标[白细胞介素-8(IL-8)、肿瘤坏死因子-α(TNF-α)和转化生长因子-β_(1)(TGF-β_(1))];比较两组治疗前1 d,治疗1、2、4周视觉模拟评分法(VAS)评分。结果研究组临床疗效优于对照组,差异有统计学意义(P<0.05)。研究组伤口好转时间、肛门水肿消失时间、出血消失时间及渗液消失时间短于对照组,差异有统计学意义(P<0.05)。治疗后,两组IL-8、TNF-α和TGF-β_(1)水平低于治疗前,且研究组低于对照组,差异有统计学意义(P<0.05)。两组不同时间点组内比较,差异有统计学意义(P<0.05);治疗1、2、4周,研究组VAS评分低于对照组,差异有统计学意义(P<0.05)。结论光子治疗仪联合藻酸盐粉在痔病患者术后康复治疗中的应用价值较高,能够提升其创面愈合速度,降低炎症因子水平,缓解疼痛,可以在临床上广泛推广和应用。Objective To investigate the effect of photon therapy apparatus combined with alginate powder on wound healing after hemorrhoidal surgery.Methods Eighty patients with emorrhoids who underwent surgery in Jiangning Hospital Affiliated to Nanjing Medical University from February to September 2020 were selected as the study subjects,they were divided into control group and study group according to the random number table method,with 40 cases in each group.The patients in control group were treated with photon therapy apparatus,and the patients in study group were treated with photon therapy apparatus combined with alginate powder.The clinical efficacy between two groups were compared;the time of wound improvement,disappearance time of anal edema,disappearance time of bleeding,and disappearance time of exudation between two groups were compared;the inflammatory indexes(interleukin-8[IL-8],tumor necrosis factor-α[TNF-α],and transforming growth factor-β_(1)[TGF-β_(1)])were compared between two groups before and after treatment;visual analog scale(VAS)scores were compared between two groups at one day before treatment and one,two weeks,and four weeks after treatment.Results The clinical efficacy of study group was better than that of control group,and the difference was statistically significant(P<0.05).The time of wound improvement,disappearance time of anal edema,disappearance time of bleeding,and disappearance time of exudation in study group were shorter than those in control group,and the differences were statistically significant(P<0.05).After treatment,the levels of IL-8,TNF-α,and TGF-β_(1) in two groups were lower than those before treatment,and study group was lower than control group,and the differences were sta-tistically significant(P<0.05).Pairwise comparison between the two groups at different time points showed statistically significant difference(P<0.05);after one,two weeks,and four weeks of treatment,VAS scores of study group were lower than those of control group,and the differences were statistic

关 键 词：光子治疗仪 藻酸盐粉 痔病 创面愈合 

分 类 号：R657.1[医药卫生—外科学]