UV light-driven asymmetric vinylogous aldol reaction of isatins with 2-alkylbenzophenones and enantioselective synthesis of 3-hydroxyoxindoles  

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作  者:Shixuan Cao Jiatian Li Taishan Yan Jie Han Zhengjie He 

机构地区:[1]State Key Laboratory of Elemento-Organic Chemistry,College of Chemistry,Nankai University,Tianjin 300071,China [2]Collaborative Innovation Center of Chemical Science and Engineering(Tianjin),Tianjin 300071,China

出  处:《Organic Chemistry Frontiers》2022年第3期643-648,共6页有机化学前沿(英文)

基  金:Financial support from the National Natural Science Foundation of China(Grant No.22171143,21472096 and J1103306)is gratefully acknowledged.

摘  要:Chiral 3-hydroxyoxindoles are biologically important molecular motifs which are frequently present in natural products and artificial compounds.Herein,we report an ultraviolet light-driven asymmetric vinylogous aldol reaction between versatile isatins and 2-alkylbenzophenones.Under mild conditions.

关 键 词:conditions ASYMMETRIC ALKYL 

分 类 号:O62[理学—有机化学]

 

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