Alkylsulfonium salts for the photochemical desulphurizative functionalization of heteroarenes  

作　　者：Xiaolong Zhu Min Jiang Xuan Li Enjie Zhu Qirong Deng Xiuyan Song Jian Lv Daoshan Yang 

机构地区：[1]Key Laboratory of Optic-electric Sensing and Analytical Chemistry for Life Science,MOE,College of Chemistry and Molecular Engineering,Qingdao University of Science and Technology,Qingdao,266042,P.R.China [2]Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology(Ministry of Education),Department of Chemistry,Tsinghua University,Beijing 100084,People’s Republic of China [3]College of Materials,Chemistry and Chemical Engineering,Hangzhou Normal University,Hangzhou,310036,P.R.China

出　　处：《Organic Chemistry Frontiers》2022年第2期347-355,共9页有机化学前沿（英文）

基　　金：supported by the Natural Science Foundation of Shandong Province(ZR2016JL012,ZR2020JQ07);the Scientific Research Foundation of Qingdao University of Science and Technology(1203043003457).

摘　　要：The development of new versatile alkylation reagents that can be transformed from diverse available chemical raw materials is highly desirable.Here,an efficient,metal-free organic photoredox-catalyzed direct alkylation of heteroarenes via a desulphurization strategy using alkylsulfonium salts as alkylation reagents under mild conditions has been described for the first time.The inexpensive and efficient organic photoredox-catalyzed method offers a new and useful strategy for constructing various biologically interesting heteroarenes in the fields of synthetic and pharmaceutical chemistry,and extends the scope of the still limited sulfonium salt photochemistry.

关 键 词：SALTS ALKYLATION sulfo 

分 类 号：O62[理学—有机化学]