包头市2022年2-3月新型冠状病毒肺炎病例临床分析  

Clinical Analysis of Covid 19 Cases in Baotou From February to March 2022

作　　者：杨勇[1] 丁丽芳[1] 姜翠英[1] 王强 白晓汉[1] 常晓悦[1] YANG Yong;DING Lifang;JIANG Cuiying;WANG Qiang;BAI Xiaohan;CHANG Xiaoyue(Respiratory and Critical Care Medicine Department,Baotou City Central Hospital,Baotou,Inner Mongolia 014040)

机构地区：[1]包头市中心医院呼吸与危重症医学科,内蒙古包头014040

出　　处：《智慧健康》2023年第13期23-29,共7页Smart Healthcare

摘　　要：目的 回顾性分析包头市2022年2-3月新型冠状病毒肺炎患者的临床资料及诊治情况,分享诊治经验。方法 收集包头市2022年2-3月份全部确诊新型冠状病毒肺炎的患者共计25例临床诊疗资料。治疗方案为:氧疗、抗凝、注射胸腺法新、俯卧位治疗、鼻腔冲洗及漱口、中药治疗,没有使用任何抗病毒药物,未使用抗菌药。出院患者继续鼻腔冲洗。结果 包头市此次新型冠状病毒肺炎患者主要临床表现为咽干咽痛(92%)、咳嗽咳痰(80%)、嗅觉味觉异常(76%),而仅56%的患者出现发热。白细胞计数、血小板计数、中性粒细胞计数、淋巴细胞计数、单核细胞计数、CRP、IL-6在不同病程阶段的差异有统计学意义(P<0.05)。淋巴细胞亚群的淋巴细胞数、T淋巴细胞数、抑制/细胞毒T淋巴细胞数、辅助/诱导T淋巴细胞数转阴后较入院时明显提升,差异有显著的统计学意义(P<0.01)。A链21例转阴病程(20.33±4.74)d,B链4例病例转阴病程(12.00±2.83)d,B链明显低于A链(P=0.003)。A链第三代及以后的病程较第一、二代短,差异具有统计学意义(P<0.05)。25例患者全部治愈出院,无死亡病例,而且出院后14d内无患者复阳。结论 新型冠状病毒肺炎的可采用非抗病毒的方式治愈。传播链靠后的患者病程相对较短。按照新型冠状病毒肺炎诊疗方案(试行第九版)的出院标准,可明显缩短住院天数。Objective To review and analyze clinical data,diagnosis and treatment of Covid 19 patients in Baotou City from February to March 2022,and share experience of diagnosis and treatment.Methods The paper collected clinical diagnosis and treatment data of a total of 25 patients diagnosed with COVID-19 in Baotou City from February to March 2022.Treatment plan included oxygen therapy,anticoagulation,thymic injection,prone position treatment,nasal irrigation and mouthwash and traditional Chinese medicine treatment,without any antiviral drugs or antibiotics.Discharged patients were treated with nasal irrigation continuously.Main clinical manifestations of COVID-19 patients in Baotou City were dry throat and sore throat(92%),cough and phlegm(80%)and abnormal smell and taste(76%),with only 56%experiencing fever.Difference in white blood cell count,platelet count,neutrophil count,lymphocyte count,monocyte count,CRP and IL-6 at different stages of the disease was statistically significant(P<0.05).Lymphocyte count,T lymphocyte count,inhibitory/cytotoxic T lymphocyte count and auxiliary/induced T lymphocyte count of lymphocyte subgroup were significantly higher after turning negative than admission,with significant statistical significance(P<0.01).21 cases of A-chain turned negative for(20.33±4.74)days,while 4 cases of B-chain turned negative for(12.00±2.83)days.Those of B-chain were significantly lower than A-chain(P=0.003).Disease course of the third and subsequent generations of A-chain was shorter than the first and second generations,difference was statistically significant(P<0.05).All 25 patients were cured and discharged without any deaths and no patients turned positive within 14 days after discharge.Conclusion Covid 19 can be cured by non antiviral methods.Patients with lower transmission chain have relatively short course of disease.According to discharge standard of diagnosis and treatment plan for novel coronavirus pneumonia(trial version 9),number of days in hospital can be reduced significantly.

关 键 词：新型冠状病毒肺炎 胸腺法新 T淋巴细胞 鼻腔冲洗 白介素6 

分 类 号：R563.1[医药卫生—呼吸系统]