盐酸奈福泮注射液与输液配伍稳定性研究  

Study on the Compatible Stability of Nefopam Hydrochloride Injection and Infusion

作　　者：赵亭 吴双俊 侯秋玲 王正雯 刘长江 尹彩霞 李慧华 黄京京 Zhao Ting;Wu Shuangjun;Hou Qiuling;Wang Zhengwen;Liu Changjiang;Yin Caixia;Li Huihua;Huang Jingjing(Shandong Fangming Pharmaceutical Group Co.,Ltd.,Dongming 274500,China)

机构地区：[1]山东方明药业集团股份有限公司,山东东明274500

出　　处：《山东化工》2023年第9期56-60,共5页Shandong Chemical Industry

摘　　要：目的:研究盐酸奈福泮注射液与输液配伍的稳定性。方法:将盐酸奈福泮注射液分别用0.9%氯化钠注射液和5%葡萄糖注射液稀释,在25℃下于0,2,4,6,8,10,12,24 h内的稳定性。结果:在上述条件下,各项指标均较稳定。结论:盐酸奈福泮注射液与0.9%氯化钠注射液和5%葡萄糖注射液配伍后,在25℃条件下,24 h内稳定。Objective:To study the stability of nefopam hydrochloride injection and infusion.Methods:Nefopam hydrochloride injection was diluted with 0.9%sodium chloride injection and 5%glucose injection respectively.The stability of nefopam hydrochloride injection was determined at 25℃within 0,2,4,6,8,10,12 and 24 hours.Results:All indexes were stable under the above conditions.Conclusion:Nefopam hydrochloride injection is stable within 24 hours at 25℃after compatibility with 0.9%sodium chloride injection and 5%glucose injection.

关 键 词：盐酸奈福泮 注射液 输液 配伍稳定性 

分 类 号：TQ469[化学工程—制药化工] R944.1[医药卫生—药剂学]