晚期食管癌放疗患者放疗损伤预防护理的最佳证据总结  

Summary of best evidence for radiotherapy injury prevention and nursing in patients with advanced esophageal cancer undergoing radiotherapy

作　　者：杨帆[1] 常娜 胡成文 Yang Fan;Chang Na;Hu Chengwen(Department of Radiotherapy,the First Affiliated Hospital of USTC,Division of Life Sciences and Medicine,University of Science and Technology of China,Hefei 230031,China)

机构地区：[1]中国科学技术大学附属第一医院西区放疗科,合肥230031

出　　处：《中华现代护理杂志》2023年第17期2268-2273,共6页Chinese Journal of Modern Nursing

基　　金：2021年安徽省护理学会科研课题重点项目(AHHL a202105);中央高校基本科研业务费专项资金资助(WK9110000188)。

摘　　要：目的总结晚期食管癌放疗患者放疗损伤预防护理的最佳证据。方法计算机检索澳大利亚乔安娜布里格斯研究所(Joanna Briggs Institute,JBI)循证卫生保健中心数据库、英国国家卫生与临床优化研究所、美国指南网、加拿大安大略省注册护士协会网站、新西兰指南协作组、PubMed、Cochrane Library、UpToDate、中国生物医学文献数据库、中国知网、万方数据库中晚期食管癌患者放疗损伤预防护理的相关证据,检索时限为建库到2022年1月31日。由2名研究者进行证据检索、质量评价和证据提取。按照JBI证据预分级及证据推荐级别系统(2014版)进行证据分级及推荐级别评定。结果共纳入11篇文献,包括系统综述2篇,指南2篇,系统评价2篇,随机对照试验3篇,类实验研究2篇。最终从口腔黏膜炎、味觉改变或丧失、营养不良、放疗性食管炎、放射性肺炎、放射性皮炎、恶心呕吐、骨髓抑制8个方面汇总28条证据。结论本研究提取的证据可以为晚期食管癌患者放疗损伤预防护理提供循证依据,各医院机构可按照实际情况对证据进行转化应用。Objective To summarize the best evidence for radiotherapy injury prevention and nursing in patients with advanced esophageal cancer undergoing radiotherapy.Methods Evidence for radiotherapy injury prevention and nursing in patients with advanced esophageal cancer undergoing radiotherapy were searched through Australian Joanna Briggs Institute(JBI)Evidence-Based Health Care Center Database,National Institute for Health and Care Excellence,National Guideline Clearinghouse,Registered Nurses'Association of Ontario,New Zealand Guidelines Group,PubMed,Cochrane Library,UpToDate,China Biomedical Literature Database,China National Knowledge Infrastructure,and Wanfang Data.The search period was from the establishment of the database to January 31,2022.Evidence retrieval,and evidence extraction were performed by 2 researchers.Evidence was graded and recommended according to the JBI evidence pre-grading system(2014 edition).Results A total of 11 articles were included,including 2 systematic reviews,2 guidelines,2 systematic assessments,3 randomized controlled trials and 2 quasi-experimental studies.A total of 28 pieces of evidence were collected from 8 aspects,including oral mucositis,taste change or loss,malnutrition,radiation-induced esophagitis,radiation pneumonitis,radiation dermatitis,nausea and vomiting,and bone marrow suppression.Conclusions The evidence extracted in this study can provide an evidence-based basis for prevention and nursing of radiotherapy injury in patients with advanced esophageal cancer,and hospitals can transform and apply the evidence according to their actualities.

关 键 词：食管肿瘤 放疗 损伤 循证护理 证据总结 

分 类 号：R473.73[医药卫生—护理学]