临床药师参与1例鼠伤寒沙门菌肠炎患儿抗感染治疗的药学实践  

Pharmaceutical Practice of Anti-Infective Treatment for a Child with Salmonella Typhimurium Enteritis by Clinical Pharmacists

作　　者：宋文琳 赵凯[2] 段露芬 Song Wenlin;Zhao Kai;Duan Lufen(Children’s Hospital of Suzhou Wujiang District,Jiangsu Suzhou 215200,China;Suzhou Municipal Hospital,Jiangsu Suzhou 215002,China)

机构地区：[1]苏州市吴江区儿童医院,江苏苏州215200 [2]苏州市立医院,江苏苏州215002

出　　处：《儿科药学杂志》2023年第7期7-10,共4页Journal of Pediatric Pharmacy

基　　金：2021年度苏州市科技发展计划,编号SKJYD2021171。

摘　　要：目的:对临床药师参与的1例鼠伤寒沙门菌肠炎患儿的抗感染治疗进行分析,为提高患儿的用药安全提供参考。方法:临床药师通过查阅文献得知鼠伤寒沙门菌感染性腹泻治愈后,通过粪便的排菌周期较长,建议临床医师及时停用抗菌药物,避免恢复期长期使用抗菌药物延长患儿的排菌周期,增加药物不良反应,甚至引发二重感染。结果:临床医师采纳药师建议,停用抗菌药物,住院期间未观察到明显药物不良反应。结论:临床药师应关注鼠伤寒沙门菌肠炎患儿的抗感染治疗疗程,提高患儿用药安全性。Objective:To analyze the anti-infective treatment for a child with Salmonella typhimurium enteritis participated by clinical pharmacists,so as to provide reference for improving the medication safety.Methods:Through literature review,the clinical pharmacists suggested that S.typhimurium infected diarrhea had a long elimination cycle through the feces after it was cured.It was recommended that clinicians stop using antibiotics in a timely manner to avoid the long-term use of antibiotics during the recovery period to prolong the elimination cycle of children,which increased adverse drug reactions and even caused secondary infection.Results:The clinicians adopted pharmacists’suggestions and stopped antibiotics administration,and no obvious adverse drug reactions were observed during hospitalization.Conclusion:Pharmacists should focus on the treatment course of anti-infective treatment for children with S.typhimurium enteritis to improve the medication safety.

关 键 词：临床药师 鼠伤寒沙门菌 抗感染 恢复期 排菌时间 

分 类 号：R969.3[医药卫生—药理学]