磁共振扩散张量成像在糖尿病周围神经病变患者胫神经与腓总神经定量分析中的应用价值  

Application of MR diffusion tensor imaging in quantitative analysis of tibal and common peroneal nerves in diabetic patients

作　　者：唐丽丽[1] 吕喆[1] 李梦参 张滨[1] 那曼丽 TANG Li-li;LV Zhe;LI Meng-shen;ZHANG Bin;NA Man-li(Department of Medical Imaging,Peking University Shougang Hospital,Beijing 100041,China)

机构地区：[1]北京大学首钢医院医学影像科,北京100041

出　　处：《川北医学院学报》2023年第7期974-976,980,共4页Journal of North Sichuan Medical College

基　　金：北京大学首钢医院2019青年基金项目(SGYYQ201910)。

摘　　要：目的:探讨磁共振扩散张量成像(DTI)在糖尿病周围神经病变(DPN)患者胫神经与腓总神经定量分析中的应用价值。方法:选取27例DNP患者为糖尿病组;另选取45名健康成人为健康组,两组均行膝关节磁共振DTI。比较两组患者胫神经与腓总神经磁共振DTI图、髌骨上缘胫神经与腓总神经各项异性分数(FA)值。结果:在轴位T1WI图像上,两组对象胫神经及腓总神经显示为圆或椭圆形,与周围肌肉组织信号相近,呈等或略低信号,其内信号均匀或稍欠均匀,边缘包裹低信号神经外膜,周围为高信号脂肪组织;糖尿病组患者DTT图显示胫神经及腓点神经粗细欠均匀,边缘毛糙,局部结构扭曲。糖尿病组患者胫神经及腓总神经FA值分别为(0.459±0.091)、(0.467±0.125);健康组患者胫神经及腓总神经FA值分别为(0.517±0.084)、(0.531±0.102),糖尿病组患者胫神经及腓总神经FA值低于健康组(P<0.05)。结论:磁共振DTI技术可定量评估DPN的胫神经及腓总神经损伤情况,为定量分析DPN提供依据。Objective:To explore the value of diffusion tensor imaging(DTI)in quantitative analysis of tibial nerve and common peroneal nerve in patients with diabetes peripheral neuropathy(DPN).Methods:27 patients with DNP were selected as diabetes group,another 45 healthy adults were selected as the health group,and both groups underwent DTI of the knee joint using magnetic resonance imaging.The magnetic resonance DTI images of the tibial and common peroneal nerves,and fractional anisotropy(FA)value's of the tibial and common peroneal nerves at the upper edge of the patella were compared between two groups.Results:On the axial T1WI images,the tibial nerve and common peroneal nerve of the two groups of subjects were round or oval,similar to the signal of the surrounding muscle tissue,showing equal or slightly low signal,the internal signal was uniform or slightly less uniform,the edge was wrapped with low signal Epineurium,and the surrounding was high signal adipose tissue.DTT images of the patients in the diabetes group showed that the thickness of the tibial and common peroneal nerves was not uniform,the edges were rough,and the local structure was distorted.The FA values of tibial nerve and common peroneal nerve in diabetic group(0.459±0.091,0.467±0.125)were lower than those in healthy adult group(0.517±0.084,0.531±0.102),and there were significant difference among the two groups(P<0.05).Conclusion:MR DTI can be used to quantitatively estimate injury of tibial and common peroneal nerves of diabetic peripheral neuropathy,to provide the basis for quantitatively analysis of diabetic peripheral neuropath.

关 键 词：糖尿病 扩散张量成像 胫神经 腓总神经 各向异性分数 

分 类 号：R445.2[医药卫生—影像医学与核医学]