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作 者:何广伟 He Guangwei(Binhai New Area Center for Disease Control and Prevention,Tianjin,300270,China)
机构地区:[1]天津市滨海新区疾病预防控制中心,天津300270
出 处:《黑龙江医学》2023年第14期1714-1716,共3页Heilongjiang Medical Journal
摘 要:目的:探讨胸部CT在抗结核板式组合药治疗肺结核患者效果评价中的应用。方法:选取2019年5月—2021年12月天津市滨海新区疾病预防控制中心收治的80例肺结核患者作为研究对象,按照随机数表法分为对照组和观察组,每组各40例。对照组采用常规药物治疗,观察组采用抗结核板式组合药治疗,两组患者治疗前后均实施胸部CT检查,比较两组患者疗效、肺结核病灶吸收情况及不良反应发生情况。结果:观察组总有效率明显高于对照组,差异有统计学意义(χ^(2)=6.275,P<0.05)。经胸部CT检查,观察组肺结核病灶吸收率明显高于对照组,差异有统计学意义(χ^(2)=4.943,P<0.05)。观察组中纳差、恶心呕吐、头痛乏力患者各2例,腹胀患者3例,不良反应发生率为22.50%(9/40);对照组中纳差、腹胀患者各3例,恶心呕吐、头痛乏力各2例,不良反应发生率为25.00%(10/40),两组患者比较,差异无统计学意义(χ^(2)=0.069,P>0.05)。结论:胸部CT在抗结核板式组合药治疗肺结核患者效果评价中的应用效果理想,有利于提升疾病诊断符合率,且能够促进患者病灶吸收、病情改善,降低其不良反应发生率。Objective:To investigate the application in the evaluation of the effectiveness of chest CT combined with anti-tuberculosis plate combinations applied in the diagnosis and treatment of patients with pulmonary tuberculosis.Methods:80 cases of pulmonary tuberculosis patients admitted to the center from May 2019 to December 2021 were selected as study subjects and divided into control group and observation group according to the random number table method,with 40 cases in each group.The control group was treated with conventional drugs and the observation group was treated with anti-tuberculosis plate combination drugs,and chest CT examination was implemented before and after treatment in both groups.The efficacy,the absorption of tuberculosis lesions and the occurrence of adverse reactions were compared between the two groups.Results:The total effective rate of the observation group was significantly higher than that of the control group,and the difference was statistically significant(χ^(2)=6.275,P<0.05).By chest CT examination,the absorption rate of pulmonary TB lesions in the observation group was significantly higher than that in the control group,and the difference was statistically significant(χ^(2)=4.943,P<0.05).In the observation group,there were 2 cases each of poor nausea,nausea and vomiting,and headache and weakness,and 3 cases of abdominal distension,with an adverse reaction rate of 22.50%(9/40).In the control group,there were 3 patients each with dyspepsia and abdominal distension,and 2 patients each with nausea and vomiting and headache and weakness,with an adverse reaction rate of 25.00%(10/40),with no statistically significant difference(χ^(2)=0.069,P>0.05).Conclusion:The application of chest CT combined with anti-tuberculosis plate combination drugs in the diagnosis and treatment of patients with pulmonary tuberculosis is ideal,which is conducive to improving the diagnostic compliance rate of the disease,and can promote the absorption of lesions,improve the condition of patients,and reduce the i
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