2017-2021年海南省手足口病重复感染病例流行特征分析  

Epidemiological characteristics of hand-foot-mouth disease(HFMD)reinfection in Hainan,2017-2021

作　　者：罗艳[1] 杜中华[1] 邱丽[1] 曾云婷 何滨[1] 陈少明[1] LUO Yan;DU Zhong-hua;QIU Li;ZENG Yun-ting;HE Bin;CHEN Shao-ming(Hainan Center for Disease Control and Prevention,Hainan 570100,China)

机构地区：[1]海南省疾病预防控制中心,海南海口570203

出　　处：《现代预防医学》2023年第12期2132-2136,共5页Modern Preventive Medicine

基　　金：海南省自然科学基金(819MS131);海南省自然科学基金(813254)。

摘　　要：目的 分析2017-2021年海南省手足口病重复感染病例的流行病学特征,为手足口病防控工作提供科学依据。方法 采用描述流行病学及空间流行病学方法分析2017-2021年海南省手足口病重复感染病例病原学特征及三间分布。结果 海南省手足口病重复感染率为9.16%,重复感染的病例发病高峰在4-7月和9-11月,13 310例重复感染病例时间间隔中位数为347 d, 85%手足口病病例在2年内发生重复感染。病例存在空间聚集性,高-高聚集区主要分布在东北部、北部及中部。重复感染年龄主要集中在3岁以下,重复感染率男(9.75%)高于女(8.25%),幼托儿童(9.97%)重复感染率高于散居儿童(9.18%),病原为其他肠道病毒发生重复感染比例最高,为46.22%。结论 海南省手足口病重复感染率较高,重复感染病例发病以低龄、男童居多,4-7月和9-11月为发病高峰,首次患病后,重复感染多在2年内发生,病例存在空间聚集性,应提高监护人的防病意识,做好幼托机构及家长的健康宣教工作,降低重复感染的风险。Objective To analyze the epidemiological characteristics of hand,foot and mouth disease(HFMD)reinfection in Hainan from 2017 to 2021,and to provide a theoretical basis for the prevention and control of HFMD in Hainan.Methods The characteristics of etiology,crowd,time,region among HFMD reinfection were Analyzed by descriptive epidemiological and spatial epidemiological methods.Results The incidence of HFMD reinfection cases in Hainan Province was 9.16%.The peaks time of HFMD reinfection cases were occurred in April to July and September to November.The median time interval of 13,310 HFMD cases with multiple infections were 347 days,and 85%cases occurred within 2 years of the first infection.The mainly distributed in the northeast,north and central regions of spatial aggregation cases with high to high concentrations.Most reinfection cases were under 3 years old.The rate of reinfection cases in males(9.75%)was higher than that in females(8.25%),and the rate of reinfection cases in childcare children(9.97%)was higher than that in diaspora children(9.18%).The highest rate of reinfection was 46.22%caused by other enteroviruses.Conclusion There was a relatively higher incidence of HFMD reinfection cases in Hainan province.Most of the patients were low age and male,with high incidence in summer and autumn.Most of the cases occurred within 2 years.There was a spatial cluster of cases.It is necessary to improve the awareness of disease prevention of guardians,and do a good job of health education in the kindergarten and parents to reduce the risk of reinfection.

关 键 词：手足口病 重复感染 流行病学特征 

分 类 号：R725.1[医药卫生—儿科]