实体器官移植受者新型冠状病毒感染诊疗专家共识(2023年版)  

Expert Consensus on the Management of COVID-19 in Solid Organ Transplant Recipients(2023 edition)

作　　者：国家传染病医学中心 中华医学会器官移植学分会 中国康复医学会器官移植康复专业委员会 王正昕[2] 郑建铭[3] 陈静瑜[4] 郑哲 霍枫 艾静文 陈文慧[8] 刘尊伟[9] 胡小莹 姜盛然 李力 何玮乔 李辉[10] 顾言阁 刘甜甜 马恩斯 牛万洁 孙超 王琲 王森[3] 汪静怡 于金洋 张法丽 朱宁骐 周晛 National Center for Infectious Diseases;Chinese Medical Association Organ Transplantation Branch,;Organ Transplantation Rehabilitation Committee of the China Society of Rehabilitation Medicine;Special Fund for Health Management of Organ Transplant Recipients of the China Organ Transplantation Development Foundation;Wang Zhengxin;Zheng Jianming;Chen Jingyu;Zheng Zhe;Huo Feng(不详;Huashan Hospital,Institute of Organ Transplantation,Fudan University,Shanghai 200040,China;Huashan Hospital,Fudan University,Shanghai 200040,China;Wuxi Peoples Hospital,Wuxi 214000,China;Fu Wai Hospital,Chinese Academy of Medical Sciences,Beijing 100037,China;Organ Transplant Recipient Health Management Special Fund,China Organ Transplant Development Foundation,Bejing 100010;General Hospital of Southern War Zone,Chinese Peoples Liberation Army Guangzhou 510000,China)

机构地区：[1]不详 [2]复旦大学附属华山医院、复旦大学器官移植研究所,上海200040 [3]复旦大学附属华山医院,上海200040 [4]无锡市人民医院,214000 [5]中国医学科学院阜外医院,北京100037 [6]中国器官移植发展基金会器官移植受者健康管理专项基金,北京100010 [7]中国人民解放军南部战区总医院,广州510000 [8]中日友好医院 [9]西安交通大学第一附属医院 [10]中日友好医院国家呼吸医学中心

出　　处：《中华移植杂志（电子版）》2023年第2期65-81,共17页Chinese Journal of Transplantation(Electronic Edition)

基　　金：上海申康医院发展中心临床三年行动计划(SHDC2020CR2021B);国家自然科学基金专项项目(82241225);上海市重大专项(HS2021SHZX001)。

摘　　要：自2019年底以来,新型冠状病毒(新冠病毒)感染大流行已席卷全球。虽然目前的新冠病毒变异株的致病性和毒力已较原始株有所下降,大多数患者预后良好,但实体器官移植(SOT)受者人群为新冠病毒感染脆弱人群,即使全程接种新冠病毒疫苗,SOT受者感染新冠病毒的住院或死亡风险依然较高。SOT受者新冠病毒感染后其临床表现、诊断和治疗均与普通人群存在很大的特殊性,需要高度关注。目前尚缺乏针对SOT受者人群可供参考的新冠病毒感染诊疗领域的指南或共识。因此,参考《新型冠状病毒诊疗方案(试行第十版)》及国内外文献,编写团队撰写了《实体器官移植受者新型冠状病毒感染诊疗专家共识(2023年版)》。本共识基于国内外新冠病毒感染的循证医学证据,并经过专家多次研讨达成一致意见后撰写成文,形成21条推荐意见,为SOT受者感染新冠病毒的诊疗提供参考。Since the end of 2019,the novel coronavirus infection pandemic has swept the world.Although the current novel coronavirus mutants have decreased in pathogenicity and virulence compared with the original strains,and most patients have a good prognosis,the solid organ transplant(SOT)recipients are vulnerable to novel coronavirus.And even with vaccination,the risk of hospitalization or death is still high in SOT recipients infected with novel coronavirus.What′s more,the clinical manifestations,diagnosis and treatment strategy of SOT recipients infected with novel coronavirus has its unique features,which need high attention.At present,there is a lack of guidelines or consensus in the diagnosis and treatment field of novel coronavirus for such a large number of SOT recipients.Therefore,referring to the"Diagnosis and treatment plan of coronavirus(Trial Version 10)"and global published literature,the writing team wrote the"Expert consensus on diagnosis and treatment of novel coronavirus infection in solid organ transplant recipients(2023 edition)".This consensus was evidence-based written and reached by experts after multiple rounds of discussions,forming 21 recommendations,providing reference for the diagnosis and treatment of SOT recipients infected with novel coronavirus.

关 键 词：实体器官移植 新型冠状病毒 诊断 治疗 

分 类 号：R511[医药卫生—内科学] R617[医药卫生—临床医学]