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作 者:范智凌[1] 谢玉国[1] 曾庆湖[1] FAN Zhiling;XIE Yuguo;ZENG Qinghu(Department of Burn Plastic Surgery,the 91811 Hospital of the PLA,Chaozhou 521000,Guangdong,China)
机构地区:[1]中国人民解放军91811部队医院烧伤整形外科,广东潮州521000
出 处:《中南医学科学杂志》2023年第3期425-428,共4页Medical Science Journal of Central South China
摘 要:目的 研究游离植皮联合负压吸引技术对烧伤后皮肤缺损创面愈合质量及美观度的影响。方法 选取180例烧伤后皮肤缺损患者,随机均分为对照组和联合组。对照组采用游离植皮技术治疗,联合组采用游离植皮联合负压吸引技术治疗。比较两组治疗情况和血清细胞间黏附分子-1(ICAM-1)、促红细胞生成素(EPO)水平。术后随访1年,比较两组创面愈合质量、创面美观度和并发症发生率。结果 联合组换药次数、肉芽生长时间、创面愈合时间、住院时间及抗感染用药时间均低于对照组(P<0.05)。术后两组ICAM-1均低于术前,EPO高于术前,且联合组较对照组更为明显(P<0.05)。联合组总有效率高于对照组,温哥华瘢痕评定量表总分低于对照组,并发症总发生率低于对照组(P<0.05)。结论 烧伤后皮肤缺损患者采用游离植皮联合负压吸引技术治疗可提高创面愈合质量,瘢痕恢复理想,可在临床推广应用。Aim Study the effect of free skin grafting combined with negative pressure suction technology on the quality and aesthetics of skin defect wound healing after burns.Methods 180 patients with skin defects after burns were randomly divided into a control group and a combination group.The control group was treated with free skin grafting technology,while the combined group was treated with free skin grafting combined with negative pressure suction technology.Compare the treatment status and serum levels of intercellular adhesion molecule-1(ICAM-1)and erythropoietin(EPO)between the two groups.Follow up for 1 year after surgery to compare the quality of wound healing,wound aesthetics,and incidence of complications between the two groups.Results The times of dressing change,growth time of granulation tissue,wound healing time,discharge time and anti-infective medication time in the combination group were lower than those in the control group(P<0.05).After surgery,ICAM-1 was lower in both groups than before surgery,EPO was higher than before surgery,and the combination group was more pronounced than the control group(P<0.05).The total effective rate of the combined group was higher than that of the control group,the total score of the Vancouver scar scale was lower than that of the control group,and the total incidence of complications was lower than that of the control group(P<0.05).Conclusion The use of free skin grafting combined with negative pressure suction technology for the treatment of skin defects after burns can improve the quality of wound healing and achieve ideal scar recovery,which can be widely applied in clinical practice.
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