微波消融治疗Klippel-Trenaunay综合征患儿边缘静脉的效果和安全性  

The curative effect and safety of endovascular microwave ablation in the treatment of the lateral marginal vein in child patients with Klippel-Trenaunay syndrome

作　　者：王亮[1] 吴长华 宋丹[1] 李静[1] 刘壮[1] 牛延丽 周洁[1] 郭磊[1,2] WANG Liang;WU Changhua;SONG Dan;LI Jing;LIU Zhuang;NIU Yanli;ZHOU Jie;GUO Lei(Department of Vascular Anomalies and Interventional Radiology,Affiliated Children’s Hospital of Shandong University(Jinan Children’s Hospital),Jinan,Shandong Province 250022,China)

机构地区：[1]山东大学附属儿童医院(济南市儿童医院)血管瘤与介入血管外科,济南250022 [2]山东省儿童健康与疾病临床医学研究中心

出　　处：《介入放射学杂志》2023年第6期590-593,共4页Journal of Interventional Radiology

摘　　要：目的探讨微波消融术治疗Klippel-Trenaunay综合征(KTS)患儿边缘静脉(LMV)的效果和安全性。方法回顾性分析2021年1月至2021年6月在山东大学附属儿童医院接受血管内微波消融闭合术治疗LMV的8例KTS患儿临床资料。统计患儿一般资料、临床疗效及术后不良反应。结果8例患儿中男女各4例,首次就诊时中位年龄为6岁(9个月~17岁),其中患肢为左下肢5例,右下肢3例。4例患儿接受LMV主干全程消融,3例为大腿段LMV消融,1例为小腿段LMV消融。术后即刻造影显示7例完全闭合,1例闭合不全,继续泡沫硬化剂注射治疗。中位随访3.9个月(2~6个月),有1例再通,表现为串珠样改变,再次消融后闭合。所有患儿术后出现不同程度的肢体肿胀,1例发生血栓性静脉炎,1例术后一过性发热。结论血管内微波消融治疗KTS患儿LMV安全有效,并发症发生率低,患儿耐受性好。Objective To discuss the efficacy and safety of endovascular microwave ablation in the treatment of lateral marginal vein(LMV)in child patients with Klippel-Trenaunay syndrome(KTS).Methods The clinical date of a total of 8 child patients with KTS,who underwent endovascular microwave ablation at the Affiliated Children’s Hospital of Shandong University of China to treat LMV with endovascular microwave ablation between January 2021 and June 2021,were retrospectively analyzed.The general data,clinical efficacy and postoperative adverse effects of the child patients were statistically analyzed.Results The 8 child patients included 4 males and 4 females.The median age of patients at their initial visit was 6 years(range of 9 months-17 years).The affected extremities included 5 left lower limbs and 3 right lower limbs.Four patients underwent total LMV ablation,three patients only received LMV ablation of the thigh,and one patient only received LMV ablation of the calf.Immediate postoperative angiography showed that complete closure of LMV was obtained in 7 patients and incomplete closure of LMV in one patient in whom foam scleroagent injection therapy had to be carried.The median follow-up time was 6 months,one patient developed recurrence,in whom the LMV presented as a string-of-beads in shape and the LMV was finally occluded after ablation again.Limb swelling of different degrees was observed in all patients,and one patient developed thrombophlebitis,and one patient had postoperative transient fever.Conclusion For the treatment of child patients with KTS,endovascular microwave ablation of LMV is clinically safe and effective,its complication rate is low and the child can be well tolerated.

关 键 词：KLIPPEL-TRENAUNAY综合征 边缘静脉 儿童 微波消融 疗效 安全性 

分 类 号：R754.1[医药卫生—皮肤病学与性病学]