水凝胶与培养基渗透性的研究进展  

Progress in research on hydrogel and medium permeability

作　　者：孙耕天(综述) 任金娜(综述) 钱明(审校)[1] SUN Gengtian;REN Jinna;QIAN Ming(Department of Oral Restoration,School of Stomatology,Jilin University,Changchun 130021,Jilin Province,China)

机构地区：[1]吉林大学口腔医院口腔修复科,吉林长春130021

出　　处：《中国生物制品学杂志》2023年第6期759-763,共5页Chinese Journal of Biologicals

基　　金：吉林省教育厅“十三五”科学技术项目(JJKH20190192KJ)。

摘　　要：凝胶作为一项新的研究领域倍受关注,并已广泛应用于组织工程、药物传递及生物感受器的研究中。水凝胶是细胞的载体,而细胞的存活与死亡是决定构建组织器官的关键之一。但细胞的活力和生物学行为由于水凝胶与培养基中营养物质的交换而受到限制。本文对水凝胶的种类、水凝胶与培养基中营养物质的交换方式及影响因素作一综述,为组织生物工程的发展和研究提供参考。As a new research field,gel has been paid more attention and widely used for studies on tissue engineering,drug delivery and biosensor.Hydrogel is the carrier of cells,while the cell survival and death are keys to the construction of tissues and organs.However,the cell viability and biological behavior are limited by the exchange of hydrogel and nutrients in medium.This review summarizes the types of hydrogel,exchange mode of hydrogel and nutrients in medium and the relevant influencing factors,which will provide a reference for the development and research of tissue bioengineering.

关 键 词：水凝胶 培养基 渗透性 细胞活性 

分 类 号：Q813[生物学—生物工程]