五味子化学成分、现代药理及临床研究进展  

Research Progress on Chemical Constituents and Pharmacological Action of Schisandra chinensis

作　　者：王艳丽 宁宇 丁莹 WANG Yanli;NING Yu;DING Ying(Heilongjiang Nursing College,Harbin 150000,China)

机构地区：[1]黑龙江护理高等专科学校,黑龙江哈尔滨150000

出　　处：《中医药信息》2023年第7期82-85,90,共5页Information on Traditional Chinese Medicine

基　　金：国家卫生健康委“十四五”规划重点课题(NHFPC102928)。

摘　　要：五味子始载于《神农本草经》,具有固涩收敛、生津止渴和补肾安神的作用,其化学成分复杂多样,具有良好的抗氧、抗肿瘤、护肝以及抗炎等药理作用。笔者通过对五味子化学成分、药理作用及临床研究进行总结发现,该药对中枢神经系统、心血管系统、消化系统以及免疫系统等具有显著的疗效,五味子中木脂素占主要成分,其次是挥发油和有机酸等,还有一些多糖类、氨基酸以及三萜类,拥有广泛的药理活性,尤其是在保护肝脏、抗肿瘤、抗氧化以及神经保护方面最为突出。Schisandra chinensis,which was firstly recorded in Shennong's Classic of Materia Medica,has complex and diverse chemical components,and has comprehensive pharmacological effects including antioxygen,anti-tumor,liver protection and anti-inflammation with its effects of astringing and converging,engendering body fluid to slake thirst,as well as tonifying Kidney and calming Shen.It is found that Schisandra chinensis has significant effects on central nervous system,cardiovascular system,digestive system and immune system by reviewing chemical components,pharmacological effects and clinic studies of the herb.Lignans are the main component in Schisandra chinensis,followed by volatile oil and organic acid,there are also polysaccharides,amino acid and trierponoides in the herb.Schisandra chinensis has extensive pharmacological activities,which epitomize in liver protection,anti-tumor and anti-oxygen.

关 键 词：五味子 化学成分 药理作用 

分 类 号：R284[医药卫生—中药学] R285[医药卫生—中医学]