实时追踪引导动态靶区放射治疗的研究进展  

Research Progress of Dynamic Target Radiotherapy Guided by Real-Time Tracking Technology

作　　者：李小波[1,2,3,4,5] 徐本华[1,2,3,4] Li Xiaobo;Xu Benhua(Department of Radiation Oncology,Hematological and Breast Malignancies of Fujian Province,Fujian Medical University Union Hospital,Fuzhou Fujian 350001,China;Fujian Key Laboratory of Intelligent Imaging and Precision Radiotherapy for Tumors,Hematological and Breast Malignancies of Fujian Province,Fujian Medical University Union Hospital,Fuzhou Fujian 350001,China;Clinical Research Center for Radiology and Radiotherapy for Digestive,Hematological and Breast Malignancies of Fujian Province,Fujian Medical University Union Hospital,Fuzhou Fujian 350001,China;School of Medical Imaging,Fujian Medical University,Fuzhou Fujian 350004,China;Department of Engineering Physics,Tsinghua University,Beijing 100084,China)

机构地区：[1]福建医科大学附属协和医院放疗科,福建福州350001 [2]福建医科大学附属协和医院福建省肿瘤智能影像与精准放疗重点实验室,福建福州350001 [3]福建医科大学附属协和医院福建省消化、血液系统与乳腺恶性肿瘤放射与治疗临床医学研究中心,福建福州350001 [4]福建医科大学医学影像学院,福建福州350004 [5]清华大学工程物理系,北京100084

出　　处：《中国医疗设备》2023年第7期152-158,共7页China Medical Devices

基　　金：福建省医学创新课题资助计划(2020CXA026)。

摘　　要：精准放疗已成为现代医学的发展趋势。三维调强放射治疗照射野大小和肿瘤一致,但人体的不自主运动会引起靶区的位置发生改变。为减小患者放疗时由于动态靶区的运动带来的剂量不确定性,常采用补偿技术,包括屏气技术、门控技术、腹部压迫技术、4D-CT技术和实时追踪技术。目前实时追踪技术对肿瘤动态靶区的放射治疗起关键性作用,大多数是借助X射线、超声、磁共振、磁定位等,可作为一种精确的运动管理方法。本文旨在对实时追踪引导动态靶区放射治疗的研究进展作一综述,以期为探寻更精准、无辐射、无创的可用于动态靶区的实时追踪技术提供研究思路。Precision radiotherapy has become the development trend of modern medicine.The size of irradiation field for threedimensional intensity modulated radiation therapy is consistent with the tumor,but the involuntary movement of the human body will cause the position of the target area to change.Compensation techniques are often used to reduce the dose uncertainty caused by dynamic target movement during radiotherapy,which including breath-holding technology,breath-gating technology,abdominal compression technique,4D-CT technology and real-time tracking technology.At present,real-time tracking technology plays a key role in radiotherapy of tumor dynamic target area.Most of them can be used as an accurate motion management method by means of X-ray,ultrasound,magnetic resonance,magnetic localization,etc.This paper aims to review the research progress of real-time tracking guided dynamic target radiotherapy,in order to provide a research idea for finding a more accurate,non-radiative and noninvasive real-time tracking technology for dynamic target.

关 键 词：实时追踪 动态靶区 精准放疗 补偿技术 

分 类 号：R144[医药卫生—公共卫生与预防医学]