肺炎支原体临床流行病学特征及其与气候环境相关性  

Clinical Epidemiological Characteristics of Mycoplasma Pneumoniae and Its Correlation with Climatic Environment

作　　者：尚晓丽[1] 倪俊学[1] 王耶盈 单娇 白娜 王松[1] SHANG Xiaoli;NI Junxue;WANG Yeying;SHAN Jiao;BAI Na;WANG Song(Dept.of Pediatrics,The 2nd Affiliated Hospital of Kunming Medical University,Kunming Yunnan 650101;School of Public Health,Kunming Medical University,Kunming Yunnan 650500,China)

机构地区：[1]昆明医科大学第二附属医院儿科,云南昆明650101 [2]昆明医科大学公共卫生学院,云南昆明650500

出　　处：《昆明医科大学学报》2023年第6期97-101,共5页Journal of Kunming Medical University

基　　金：昆明医科大学第二附属医院院内科技计划项目(2019ky002)。

摘　　要：目的研究儿童肺炎支原体(mycoplasma pneumoniae,MP)感染流行病学特征及其与气象环境的相关性。方法回顾性分析2020年1月至2021年12月因急性呼吸道感染入住昆明医科大学第二附属医院的患儿,采集血液进行特异性MP IgM、IgG双抗体滴度测定,同时收集环境气象因素。MP感染患儿临床流行病学特征使用描述分析,相关性分析使用Logistic回归,采用逐步后退Wald法建立关系模型。结果1260例检验样本中,MP阳性率32.46%,女性患儿和男性患儿MP检测阳性率分别为37.31%和28.96%,差异有统计学意义(χ^(2)=9.752,P<0.05);婴儿MP感染率显著低于其他年龄段儿童(χ^(2)=67.68,P<0.05);冬季检出率显著高于其他季节(χ^(2)=31.089,P<0.05);月累积降水量(P=0.001)、PM2.5(P<0.001)和NO2(P<0.001)显著增加MP感染的风险。结论昆明地区儿童MP感染与年龄、性别、季节和气象环境因素密切相关。Objective To explore the epidemiological characteristics of Mycoplasma pneumoniae(MP)infection in children and the association between MP infection and meteorological elements.Methods Children admitted to the Second Affiliated Hospital of Kunming Medical University from January 2020 to December 2021 due to acute respiratory tract infection were retrospectively analyzed.Blood samples were collected for specific MP IgM and IgG double antibody titers,and environmental meteorological factors data were also collected.Descriptive statistics were used for clinical epidemiological characteristics of children with MP infection,logistic regression was used for correlation analysis,and regression Wald method was used to establish a relationship model.Results The positive rate of MP was 32.46%in 1260 test samples.The positive rates of MP in female and male children were 37.31%and 28.96%,respectively,and the difference was statistically significant(χ^(2)=9.752,P<0.05).The MP infection rate in infants was significantly lower than that in other age groups(χ^(2)=67.68,P<0.05).The detection rate in winter was significantly higher than that in other seasons(χ^(2)=31.089,P<0.05).Monthly cumulative precipitation(P=0.001),PM2.5(P<0.001),and NO2(P<0.001)significantly increased the risk of MP infection.Conclusion MP infection in children in Kunming was significant associated with age,sex,season and meteorological evironment.

关 键 词：儿童 肺炎支原体 流行病学 气象因素 

分 类 号：R725.6[医药卫生—儿科]