自拟消食止咳方对食滞胃脘型咳嗽患者咳嗽积分和临床疗效的影响  

Effects of Self-made Xiaoshi Zhike Formula on Cough Score and Clinical Efficacy of Patients with Cough of Epigastric Food Stagnation

作　　者：沈丽萍 孙婧 丁德秭 王丹 SHEN Liping;SUN Jing;DING Dezi;WANG Dan(Jiujiang Hospital of Traditional Chinese Medicine,Jiangxi Province,Jiujiang 332000,China)

机构地区：[1]江西省九江市中医医院,江西九江332000

出　　处：《中国医学创新》2023年第18期75-79,共5页Medical Innovation of China

基　　金：江西省中医药管理局科技计划课题(2021A295)。

摘　　要：目的:探究自拟消食止咳方对食滞胃脘型咳嗽患者咳嗽和临床疗效的影响。方法:选取2020年1月-2022年9月于九江市中医医院门诊就真的80例食滞胃脘型咳嗽患者,按照随机数字表法分为治疗组(n=40)和对照组(n=40)。对照组予保和丸联合肺力咳治疗,治疗组给予自拟消食止咳方治疗。比较1个疗程后两组患者的临床有效率、治疗组不同年龄段及不同病程的临床疗效、中医症状积分及炎症指标[C反应蛋白(CRP)、红细胞沉降率(ESR)、嗜酸性粒细胞(EOS)]变化情况,记录治疗期间不良反应发生情况。结果:治疗后,治疗组临床总有效率高于对照组(P<0.05);治疗后,青中年组临床效果虽高于老年组,但差异无统计学意义(P>0.05);治疗后,急性组、亚急性组、慢性组临床有效率两两相比,差异均无统计学意义(P>0.05);治疗后,两组中医症状积分(咳嗽、咳痰、脘腹胀满、纳呆呃逆、恶心呕吐、嗳腐吞酸)均显著降低(P<0.05),且治疗组治疗后积分均明显低于对照组,差异均有统计学意义(P<0.05);治疗后,两组血清CRP、ESR、EOS水平均下降(P<0.05),且治疗组治疗后上述指标均低于对照组,差异均有统计学意义(P<0.05);两组治疗期间均未见明显不良反应。结论:自拟消食止咳方治疗食滞胃脘型咳嗽临床效果更佳,能明显减轻患者症状及炎症反应。Objective:To explore the effects of self-made Xiaoshi Zhike Formula on the cough score and clinical efficacy of patients with cough of epigastric food stagnation.Method:A total of 80 patients with cough of epigastric food stagnation in Outpatient Department of Jiujiang Hospital of Traditional Chinese Medicine from January 2020 to September 2022 were selected and divided into treatment group(n=40)and control group(n=40)according to the random number table method.The control group was treated with Baohe Pills combined with Feilike,while the treatment group was given self-made Xiaoshi Zhike Formula.The clinical effective rate,clinical efficacy of treatment group in different age groups and different courses of disease,scores of TCM symptoms and inflammatory indicators[C reactive protein(CRP),erythrocyte sedimentation rate(ESR),eosinophil(EOS)]of the two groups after 1 course of treatment were compared,and the adverse reactions during treatment were recorded.Result:After treatment,the total effective rate of the treatment group was higher than that of the control group(P<0.05).After treatment,the clinical effect of the young and middle-aged group was higher than that of the old group,but the difference was not statistically significant(P>0.05);after treatment,there was no statistical difference in the clinical effective rate between any two groups of acute group,subacute group and chronic group(P>0.05).The scores of TCM symptoms(cough,expectoration,abdominal fullness and distention,anorexia and hiccup,nausea and vomiting,putrid belching and acid swallowing)in both groups were significantly decreased after treatment(P<0.05),and the scores in treatment group after treatment were significantly lower than those in control group(P<0.05).After treatment,the levels of serum CRP,ESR and EOS in the two groups were reduced(P<0.05),and the above indicators in treatment group were lower than those in control group after treatment(P<0.05).No obvious adverse reactions were observed in both groups during treatment.Conclusion:Self-m

关 键 词：自拟消食止咳方 咳嗽 食滞胃脘型 中医症状积分 炎症反应 

分 类 号：R256.11[医药卫生—中医内科学]