Oxidative thiocyanation of allylic alcohols:an easy access to allylic thiocyanates with K_(2)S_(2)O_(8) and NH_(4)SCN  

作　　者：Keyuan Zhang Tianbing Liang Yulong Wang Chonglong He Mingyou Hu Xin-Hua Duan Le Liu 

机构地区：[1]School of Chemistry,Xi’an Key Laboratory of Sustainable Energy Materials Chemistry,MOE Key Laboratory for Nonequilibrium Synthesis and Modulation of Condensed Matter,Xi’an Jiaotong University,Xi’an 710049,China

出　　处：《Organic Chemistry Frontiers》2022年第4期966-972,共7页有机化学前沿（英文）

基　　金：L.Liu thanks the National Natural Science Foundation of China(21901199);Xi’an Jiaotong University(7121192002)for financial support.

摘　　要：A practical method for the synthesis of allylic thioacyanates from allylic alcohols was disclosed employing K_(2)S_(2)O_(8) as the oxidant and NH_(4)SCN as the thiocyanate source.Without introducing a leaving group in advance,a series of disubstituted and monosubstituted allylic thiocyanate compounds were obtained in moderate to good yields.This transition metal-free method features mild reaction conditions,broad sub-strate scope and operational simplicity.The potential application of this method was demonstrated by some derivatization reactions of the product and mechanistic investigation indicated that a radical process is involved.

关 键 词：ALCOHOLS SIMPLICITY substituted 

分 类 号：O62[理学—有机化学]