1156例高尿酸血症患者中医体质分布特点及危险因素分析  

Characteristics of traditional Chinese medicine constitution distribution and analysis of risk factors of 1156 cases of hyperuricemia

作　　者：曹凤娇[1] 侯秀娟[1] CAO Feng-jiao;HOU Xiu-juan(Dongfang Hospital,Beijing University of Chinese Medicine,Beijing 100078,China)

机构地区：[1]北京中医药大学东方医院,北京100078

出　　处：《中华中医药杂志》2023年第6期2974-2979,共6页China Journal of Traditional Chinese Medicine and Pharmacy

摘　　要：目的:探讨1156例高尿酸血症患者中医体质分布特点并分析其危险因素。方法:将2018年1月至2021年8月在北京中医药大学东方医院体检科行血尿酸检查并进行中医体质辨识的体检者作为观察对象,收集年龄、性别、身体质量指数、血糖、血脂等体检资料,有效病例共5844例,其中高尿酸血症1156例,观察高尿酸血症患者中医体质分布情况并通过Logistic回归分析筛选影响因素。结果:高尿酸血症患者的体质分布占比为湿热质>痰湿质>气虚质>阴虚质>阳虚质>气郁质>平和质>特禀质>血瘀质。痰湿质、湿热质在男性与女性高尿酸血症患者体质中占比均高,差异无统计学意义。18~39岁及40~59岁高尿酸血症患者均以湿热质占比最高(P<0.05)。痰湿质、湿热质、性别、身体质量指数、饮酒史、脂肪肝、肌酐、甘油三酯、低密度脂蛋白胆固醇、同型半胱氨酸、谷丙转氨酶是高尿酸血症的独立危险因素(P<0.01)。结论:湿热质、痰湿质是高尿酸血症的高发体质类型,痰湿质、湿热质、性别、身体质量指数、饮酒史、脂肪肝、肌酐、甘油三酯、低密度脂蛋白胆固醇、同型半胱氨酸、谷丙转氨酶是高尿酸血症独立危险因素。Objective:To investigate the characteristics of traditional Chinese medicine(TCM)constitution and analyze the risk factors in 1156 patients with hyperuricemia.Methods:Medical examiners who underwent blood uric acid examination and TCM constitution from January 2018 to August 2021 at the Department of Physical Examination,Dongfang Hospital,Beijing University of Chinese Medicine were used as observation subjects to collect age,gender,body mass index,blood glucose,blood lipids and other physical examination data,with a total of 5844 valid cases,including 1156 cases of hyperuricemia,to observe the distribution of body mass in hyperuricemia and the factors were screened by Logistic regression analysis.Results:The distribution of body types in patients with hyperuricaemia was damp-heat constitution>phlegm-dampness constitution>qi deficiency constitution>yin deficiency constitution>yang deficiency constitution>qi depression constitution>peace constitution>special constitution>blood stasis constitution.The proportion of phlegm-dampness constitution and damp-heat constitution was high in both male and female patients with hyperuricemia,with no statistically significant difference.The highest proportion of HUA patients aged 18-39 years and 40-59 years had damp-heat constitution(P<0.05).Phlegm-dampness constitution,damp-heat constitution,gender,body mass index,history of alcohol consumption,fatty liver,creatinine,triglycerides,LDL cholesterol,homocysteine and ghrelin were independent risk factors for hyperuricemia(P<0.01).Conclusion:Damp-heat constitution and phlegm-dampness constitution are the most prevalent body type for hyperuricaemia.Phlegm-dampness constitution,damp-heat constitution,gender,body mass index,history of alcohol consumption,fatty liver,creatinine,triglycerides,low-density lipoprotein cholesterol,homocysteine and ghrelin are independent risk factors for hyperuricaemia.

关 键 词：高尿酸血症 湿热质 痰湿质 治未病 危险因素 

分 类 号：R259[医药卫生—中西医结合]