S-triggered Schmidt-type rearrangement of vinyl azides to access N-aryl-(trifluoromethylsulfinyl) acetamides  

作　　者：Zhenhua Liu Tian Yu Longhua Li Wei Fu Xingxing Gan Huimin Chen Wen Gao Bo Tang 

机构地区：[1]College of Chemistry,Chemical Engineering and Materials Science,Collaborative Innovation Center of Functionalized Probes for Chemical Imaging in Universities of Shandong,Key Laboratory of Molecular and Nano Probes,Ministry of Education,Institute of Biomedical Sciences,Shandong Normal University,Jinan 250014,P.R.China [2]Department of Pharmacy,Zibo Central Hospital,Zibo 255000,P.R.China

出　　处：《Organic Chemistry Frontiers》2022年第5期1241-1246,共6页有机化学前沿（英文）

基　　金：This work was supported by the National Natural Science Foundation of China(21976112 and 21775092);the National Key R&D Program of China(2019YFA0210100);the Major Science and Technology Innovation Project of Shandong Province(2021ZDSYS09);the Natural Science Foundation of Shandong Province of China(ZR2021MB031 and ZR2020JQ10);the Key Research and Development Program of Shandong Province(2018YFJH0502);the China Postdoctoral Science Foundation(2020M682204).

摘　　要：A novel S-induced Schmidt-type rearrangement of vinyl azides with CF_(3)SO_(2) Na is reported,which is mediated by triphosgene(BTC)under mild reaction conditions.A wide range of N-arylated 2-(trifluoro-methylsulfinyl)acetamides,for the first time,were successfully obtained in good yields,through sequential trifluoromethylsulfinylation and aryl 1,2-migration.

关 键 词：conditions REARRANGEMENT AZIDE 

分 类 号：O62[理学—有机化学]