外泌体circRNAs在银屑病发病机制中的研究进展  

Research progress of exosomal circRNAs in psoriasis

作　　者：罗辉清 马娟[1] 付超 乔锰 辛琳琳 LUO Huiqing;MA Juan;FU Chao;QIAO Meng;XIN Linlin(Weifang Medical University,Weifang 261053,China;Department of Dermatology,The First Affiliated Hospital of Shandong First Medical University,Jinan 250014,China)

机构地区：[1]潍坊医学院,潍坊261053 [2]山东第一医科大学第一附属医院皮肤科,济南250014

出　　处：《中国麻风皮肤病杂志》2023年第8期619-624,共6页China Journal of Leprosy and Skin Diseases

基　　金：国家自然科学基金(编号:8207120270)。

摘　　要：CircRNAs被证实在外泌体中富集并稳定表达,其参与银屑病发病机制中细胞间选择性地包装、分泌和转移,调节银屑病的许多特征,如细胞增殖、血管生成、免疫反应。本文综述了外泌体circRNAs在银屑病发病机制中的相关研究进展。CircRNAs have been confirmed to be enriched and stably expressed in exosomes,and are involved in the cells selective packaging,secretion,and metastasis in the pathogenesis of psoriasis,regulating many features of psoriasis,such as cell proliferation,angiogenesis,and immune response.Herein,we sumarize the related research progress of exosomal circRNAs in psoriasis in this paper.

关 键 词：外泌体 CircRNAs 外泌体circRNAs 银屑病 

分 类 号：R758.63[医药卫生—皮肤病学与性病学]