IgA nephropathy associated with Crohn's disease  

作　　者：Hiroshi Tamura 

机构地区：[1]Department of Pediatrics,Kumamoto University,Kumamoto 8608556,Japan

出　　处：《World Journal of Methodology》2023年第3期67-78,共12页世界方法学杂志

摘　　要：The relationship between IgA nephropathy(IgAN)and Crohn’s disease was reported.IgAN is the most common primary glomerulonephritis and one of the leading causes of chronic kidney disease and end-stage renal failure,and up to 50%of cases progressed to end-stage renal disease within 25 years after IgAN diagnosis.However,specific and effective therapeutic strategies are still lacking.In this review,we discuss the possibility of the mechanism involved in IgAN associated with Crohn’s disease based on the findings of basic and clinical studies.Although the etiology of IgAN associated with Crohn’s disease is not permanent and various factors are thought to be involved,the stabilization of the disease condition of Crohn’s disease is believed to help treat IgAN.

关 键 词：Crohn’s disease IgA nephropathy Immunological abnormalities Mucosalassociated lymphoid tissue Gut-associated lymphoid tissue Nasopharynx-associated lymphoid tissue 

分 类 号：R69[医药卫生—泌尿科学]