Characterization and risk factors for unexplained female infertility in Sudan:A case-control study  

作　　者：Abdullah Abdulslam Abdullah Musa Ahmed Adesina Oladokun 

机构地区：[1]Reproductive Health Sciences Program,Pan African University Life and Earth Sciences Institute,University of Ibadan,Ibadan 119,Oyo state,Nigeria [2]Department of Obstetrics and Gynecology,College of Medicine,University of Ibadan,Ibadan 119,Oyo state,Nigeria [3]Department of Biomedical Sciences,Faculty of Veterinary Sciences,University of Gadarif,Al-Gadarif 32211,Sudan [4]Department of Veterinary Surgery,Faculty of Veterinary Medicine,AL-Salam University,Al-fula 120,West Kordofan,Sudan

出　　处：《World Journal of Methodology》2023年第3期98-117,共20页世界方法学杂志

摘　　要：BACKGROUND Female infertility with unknown causes(unexplained)remains one of the mysteries in the reproductive health field,where the diagnostic evidence is still weak and the proposed treatments still work with unknown methods.However,several studies have proposed some possible causes and risk factors for unexplained female infertility.AIM To characterize and identify factors associated with unexplained infertility in Sudanese women.METHODS A matched(age and body mass index)case-control study was conducted from March 2021 to February 2022.The study samples were 210 women with unexplained infertility(UI)and 190 fertile women of reproductive age who were attending the maternity hospitals and fertility clinics in Khartoum,Sudan.The risk factors of unexplained infertility were identified using a structured,pretested questionnaire containing information on socio-demographic variables,anthropometrics,clinical diagnosis of infertility,behavioral factors,physical activity assessment,diversity,and consumption of different food groups by the study participants.RESULTS The results showed a higher proportion of women diagnosed with UI were residents of rural areas than controls(21.4%vs 11.1%,P<0.05),and previous miscarriages and/or abortions were more common in fertile women compared with infertile women(13.16%vs 5.71%,P<0.05).Additionally,infertile women had a significantly(P<0.05)higher proportion of family history of infertility(explained and unexplained)compared with controls.Finally,after controlling for the effects of potentially confounding variables using multivariable logistic regression analysis,only marital status,family history of infertility,use of modern contraceptives,smoking,caffeine consumption,physical activity level,meals consumed,other vitamin-A-rich fruits and vegetables,and other vegetables were found to be significant(P<0.05)factors associated with unexplained infertility among Sudanese women.CONCLUSION Married women with a family history of infertility who smoke and consume a high amount of caffeine,

关 键 词：Unexplained infertility Sudanese women Risk factors Dietary diversity Physical activity level 

分 类 号：R56[医药卫生—呼吸系统]