Role of platelet-rich plasma in the treatment of rotator cuff tendinopathy  

作　　者：Ausberto Velasquez Garcia Liborio Ingala Martini Andres Franco Abache Glen Abdo 

机构地区：[1]Department of Orthopedic Surgery,Clínica Universidad de los Andes,Santiago 7620157,Chile [2]Department of Orthopedic Surgery,Hospital IVSS Dr.Luis Ortega,Porlamar 6301,Venezuela [3]Department of Orthopedic Surgery,Hospital Clinicas del Este,Los Robles 6301,Venezuela [4]Department of Orthopedic Surgery,Hospital de Especialidades Guayaquil MSP,Guayaquil 090101,Ecuador [5]Department of Graduate Medical Education,Internal Medicine Residence Program,New York Medical College at St.Mary’s and St.Clare’s,Passaic,NJ 07055,United States

出　　处：《World Journal of Orthopedics》2023年第7期505-515,共11页世界骨科杂志（英文版）

摘　　要：Shoulder pain is a common musculoskeletal complaint,and rotator cuff(RC)pathologies are one of the main causes.The RC undergoes various tendinopathic and avascular changes during the aging process.Other degenerative changes affecting its healing potential make it an appealing target for biological agents.Platelet-rich plasma(PRP)has demonstrated the potential to deliver a high concentration of several growth factors and anti-inflammatory mediators,and its clinical use is mainly supported by experiments that demonstrated its positive effect on muscle,ligaments,and tendinous cells.This review aimed to specify the role of PRP and its future applications in RC tendinopathies based on the current clinical evidence.Due to the different characteristics and conflicting outcomes,clinicians should use PRP with moderate expectations until more consistent evidence is available.However,it is reasonable to consider PRP in patients with contraindications to corticosteroid injections or those with risk factors for inadequate healing.Its autologous origin makes it a safe treatment,and its characteristics make it a promising option for treating RC tendinopathy,but the efficacy has yet to be established.

关 键 词：Rotator cuff TENDINOPATHY Platelet-rich plasma Shoulder pain Nonoperative treatment INJECTABLES 

分 类 号：R686[医药卫生—骨科学]