Evidence relating cigarette,cigar and pipe smoking to lung cancer and chronic obstructive pulmonary disease:Meta-analysis of recent data from three regions  

作　　者：Peter Nicholas Lee Katharine J Coombs Jan S Hamling 

机构地区：[1]Medical Statistics and Epidemiology,P.N.Lee Statistics and Computing Ltd.,Sutton SM25DA,Surrey,United Kingdom [2]Statistics,P.N.Lee Statistics and Computing Ltd,Sutton SM25DA,Surrey,United Kingdom [3]Statistics,RoeLee Statistics Ltd,Sutton SM25DA,United Kingdom

出　　处：《World Journal of Meta-Analysis》2023年第5期228-252,共25页世界荟萃分析杂志

摘　　要：BACKGROUND There is a need to have up-to-date information for various diseases on the risk related to the use of different smoked products and the use of other nicotinecontaining products.Here,we contribute to the information pool by presenting up-to-date quantitative evidence for North America,Europe and Japan and for both lung cancer and chronic obstructive pulmonary disease(COPD)on the relative risk(RR)relating to current vs never product use for each of the three smoked tobacco products,cigarettes,cigars and pipes.AIM To estimate lung cancer and COPD current smoking RRs for the three products using recent data for the three regions.METHODS Publications in English from 2010 to 2020 were considered that,based on epidemiological studies in the three regions,estimated the current smoking RR of lung cancer and/or COPD for one or more of the three products.The studies should involve at least 100 cases of the disease considered,not be restricted to specific lung cancer types or populations with specific medical conditions,and should be of cohort or nested case-control study design or randomized controlled trials.Literature searches were conducted on MEDLINE separately for lung cancer and for COPD,examining titles and abstracts initially,and then full texts.Additional papers were sought from reference lists of selected papers,reviews and metaanalyses.For each study identified,the most recent available data on each product were entered on current smoking,as well as on characteristics of the study and the RR estimates.Combined RR estimates were derived using random-effects meta-analysis.For cigarette smoking,where far more data were available,heterogeneity was studied by a wide range of factors.For cigar and pipe smoking,a more limited heterogeneity analysis was carried out.Results were compared with those from previous meta-analyses published since 2000.RESULTS Current cigarette smoking:For lung cancer,44 studies(26 North American,14 European,three Japanese,and one in multiple continents),gave an overall estimate of 1

关 键 词：Cigarettes CIGARS Pipes Lung cancer META-ANALYSIS Review 

分 类 号：R56[医药卫生—呼吸系统]