强脉冲光联合点阵CO_(2)激光治疗皮肤光老化疗效分析  

Efficacy Analysis of Intense Pulsed Light Combined with Fractional CO_(2)Laser in the Treatment of Skin Photoaging

作　　者：金星姬[1] 刘喜平[1] 王幼学 杨秀敏[1] JIN Xingji;LIU Xiping;WANG Youxue;YANG Xiumin(Department of Dermatology and Venereology,Beijing Tongren Hospital Affiliated to Capital Medical University,Beijing 100730,China)

机构地区：[1]首都医科大学附属北京同仁医院皮肤性病科,北京100730

出　　处：《中国美容医学》2023年第6期60-64,共5页Chinese Journal of Aesthetic Medicine

摘　　要：目的:探究强脉冲光联合点阵CO_(2)激光在光老化患者皮肤中的应用效果。方法:选取2020年6月-2022年7月笔者医院收治的135例光老化患者为研究对象,随机分为观察组(45例)、点阵CO_(2)激光组(45例)及强脉冲光组(45例),其中点阵CO_(2)激光组给予点阵CO_(2)激光治疗,强脉冲光组给予强脉冲光治疗,观察组给予强脉冲光联合点阵CO_(2)激光治疗。比较三组光老化患者皮肤质地、屏障功能及色素沉着情况。结果:观察组治疗总有效率(93.33%)、面部皮肤色素沉着治疗的总有效率、安全性、治疗舒适度、近期美观度及远期效果维持度评分显著高于点阵CO_(2)激光组(75.56%)、强脉冲光组(73.33%);点阵CO_(2)激光组与强脉冲光组比较差异无统计学意义(P>0.05)。与治疗前比较,三组治疗后皮肤色斑、纹理、皱纹、毛孔、紫质评分均显著降低,且观察组显著低于强脉冲光组及点阵CO_(2)激光组(P<0.05);与治疗前比较,治疗后观察组皮肤pH值显著降低,且明显低于强脉冲光组、点阵CO_(2)激光组。与治疗前比较,三组治疗后经皮水分丢失显著降低,皮肤含水量、油脂含量显著升高,且观察组改善效果明显强脉冲光组、点阵CO_(2)激光组(P<0.05);观察组不良反应的总发生率显著低于点阵CO_(2)激光组、强脉冲光组(P<0.05),点阵CO_(2)激光组与强脉冲光组比较差异无统计学意义(P>0.05)。结论:强脉冲光联合点阵CO_(2)激光治疗光老化患者可有效改善患者皮肤质地,修复皮肤屏障,减少皮肤色素沉着,效果显著。Objective To investigate the application intense pulsed light combined with fractional laser in the skin improvement of photoaging patients.Methods From June 2020 to July 2022,135 patients with photoaging who were admitted to the author's hospital were selected as research objects,and randomly divided into an observation group(45 cases),fractional CO_(2)laser group(45 cases),and intense pulsed light group(45 cases),the fractional CO_(2)laser group was treated with fractional CO_(2)laser,the intense pulsed light group was treated with intense pulsed light,and the observation group was treated with intense pulsed light combined with fractional CO_(2)laser.The skin texture,barrier function and pigmentation of the two groups were compared.Results Observation group total efiective rate(93.33%),facial skin pigmentation treatment,the total efiective rate of treatment,safety,comfort,beautiful recent and long-term efiect maintain rating is significantly higher than fractional CO_(2)laser group(75.56%),the intense pulsed light group(73.33%).Fractional CO_(2)laser and intense pulsed light group had no difierence(P>0.05).Three groups after treatment compared with before treatment,the skin color,texture,wrinkles and pores,purple quality score were significantly lower,and the observation group was significantly lower than intense pulsed light group and fractional CO_(2)laser group(P<0.05).Compared with before treatment,the skin pH value decreased significantly after treatment group,and significantly lower than the intense pulsed light group,fractional CO_(2)laser group.Compared with before treatment,three groups of percutaneous moisture loss decreased significantly after treatment,the marked increase in skin moisture content,oil content,and the observation group improved obviously intense pulsed light,fractional CO_(2)laser group(P<0.05).Observation group had a significantly lower than the total incidence of adverse reactions fractional CO_(2)laser,the intense pulsed light group(P<0.05),fractional CO_(2)laser and the intense p

关 键 词：光老化 点阵CO_(2)激光 强脉冲光 皮肤质地 皮肤屏障功能 色素沉着 

分 类 号：R616.4[医药卫生—外科学]