老年高血压住院患者肌肉减少症调查及影响因素分析  

Investigation and analysis of infuencing factors of sarcopenia in elderly inpatients with hypertension

作　　者：郁云兰 吕万勇 易海维[1] Yu Yunlan;Lyu Wanyong;Yi Haivei(Department of Clinieal Nutrition the First People's Hospital of Lianyungang,Lianyungang 22200.Jiangsu,China;Geriatric Nutrition Professional Comite of Gerontology Society in Jiangsu Province,Nanjing 210000,Jiangsu,China)

机构地区：[1]连云港市第一人民医院临床营养科,江苏连云港222000 [2]江苏省老年学学会老年营养专业委员会,江苏南京210000

出　　处：《肿瘤代谢与营养电子杂志》2023年第3期389-394,共6页Electronic Journal of Metabolism and Nutrition of Cancer

基　　金：江苏省老年学学会老年健康科研基金(20210127)。

摘　　要：目的了解老年高血压住院患者肌肉减少症的检出情况,并分析高血压患者发生肌肉减少症的相关影响因素。方法选取连云港市第一人民医院心内科2021年1月1日至11月30日期间住院的老年高血压患者415例,收集基本资料、人体测量学资料及血生化指标等,并进行营养筛查、人体成分分析。根据肌肉减少症诊断标准,将患者分为肌肉减少症组和非肌肉减少症组,比较两组相关指标,分析影响肌肉减少症发生的因素。结果本研究中有57例患者诊断为肌肉减少症,检出率为13.7%。肌肉减少症患者(n=57)与非肌肉减少症患者(n=358)的年龄、活动方式、高血压等级、微型营养评定简表(MNASF)评分、营养风险筛查2002评分等方面存在差异(P<0.05)。肌肉减少症患者低密度脂蛋白胆固醇、体质指数(BMI)、内脏脂肪面积、基础代谢率、相位角均低于非肌肉减少症患者(P<0.05),而收缩压、舒张压高于非肌肉减少症患者(P<0.05)。肌肉减少症患者体质指数(BMI)、内脏脂肪面积、基础代谢率、相位角均低于非肌肉减少症患者(P<0.05)。多因素Logistic回归分析显示,年龄、舒张压、BMI、MNA-SF评分是肌肉减少症发生的独立影响因素(P<0.05)。结论高龄、舒张压升高是肌肉减少症发生的危险因素,超重、肥胖、无营养不良是保护因素;肌肉减少症导致高血压患者部分体成分指标降低,营养风险更高。Objective To understand the detection rate of sarcopenia in hospitalized patients with bypertension,and to explore the relationship between sarcopenia and hyperesion and to analyze risk factors for the occurence of sarcopenia in hypertensive patients.Method 415 elderly patients with hypertension from cardiology department of the first people's hospital of Lianyungang between January 1,2021,and November 30,2021,were selected according to the inclusion criteria The patients'basic information,blod indexes,nutritional screening,anthopometary data and body composition analysis data were collected.All patients were divided into sarcopenia group(n=57)and non-sarcopenia goup(n=358)according to the diagnostic criteria for sarcopenia.The relevant indieators of the two groups were compared and the factors that afeted the ocurrence of sarcopenia were analyzed.Result In this study,57 patients were dignosed with sarcopenia.The detection rate of sarcopenia in elderly hypertension was 13.7%。There were statistically significant dffrerences in age,activity mode,the grade of hypertension,the score of MNA--SF and the soore of NRS 2002.between sarcopenia group and non-sarcopenia group(P<0.05).LDL-C,BMI,visceral fat area,bausal metabolic rate,and phase in sarcopenia group were smaller than those in non--sarcopenia group(P<0.05).Systolic blood pressure and diastolie blood pressure were higher than those in non-sarcopenia group(P<0.05).Multivariate Logistic regression analysis showed that systolie blood pressure,activity mode,the grade of hypertension,LDL C,and the score of NRS 2002 were not corelated with saropenia(P>0.05).Age,diastolic blood pressure,BMI,and the score of MNA-SF were the infuencing factors of saropenia in elderly patients with hypertension.Condlusion Advanced age and a high diastolic blood pressure are the risk factors for the occurence of saropenia in the elderly patients with hypertension,while overweight,obesity and non-malutrition are the protective factors of hypertension without saropenia.Sarcopenia results in

关 键 词：高血压 肌肉减少症 人体成分 

分 类 号：R544.1[医药卫生—心血管疾病] R685[医药卫生—内科学]