加味三子养亲汤治疗急性发作期慢阻肺患者的临床疗效探讨  

Exploring the Clinical Efficacy of Jiawei Sanzi Yangqin Decoction in Treating Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease

作　　者：张持萍 倪苏侠 王君君 ZHANG Chiping;NI Suxia;WANG Junjun(Department of Traditional Chinese Medicine,Suqian Hospital Affiliated to Xuzhou Medical University(Suqian Hospital of Nanjing Gulou Hospital Group),Suqian,Jiangsu Province,223800 China;Department of Emergency Medicine,Suqian Hospital Affiliated to Xuzhou Medical University(Suqian Hospital of Nanjing Gulou Hospital Group),Suqian,Jiangsu Province,223800 China)

机构地区：[1]徐州医科大学附属宿迁医院(南京鼓楼医院集团宿迁医院)中医科,江苏宿迁223800 [2]徐州医科大学附属宿迁医院(南京鼓楼医院集团宿迁医院)急诊内科,江苏宿迁223800

出　　处：《中外医疗》2023年第17期180-183,187,共5页China & Foreign Medical Treatment

摘　　要：目的探讨加味三子养亲汤治疗急性发作期慢性阻塞性肺疾病的临床效果。方法方便选取2020年1月—2022年1月南京鼓楼医院集团宿迁医院中医科收治的78例急性发作期慢性阻塞性肺疾病患者为研究对象,以随机数表法将其分为治疗组(39例)和对照组(39例),对照组以常规西药进行治疗,治疗组在基础上联合中药汤剂加味三子养亲汤治疗,分析治疗效果、中医症状、肺功能改善情况与药物不良反应。结果治疗组治疗总有效率(92.31%)高于对照组,差异有统计学意义(χ^(2)=4.523,P<0.05);两组经治疗后,中医证候积分(气喘、胸闷、咳嗽、咳痰)均得到降低,且治疗组气喘积分(1.09±0.03)分、胸闷积分(1.23±0.14)分、咳嗽积分(1.45±0.10)分、咳痰积分(1.12±0.13)分均低于对照组,差异有统计学意义(t=58.566、28.986、29.747、29.092,P<0.05);两组治疗后FVC、FEV1较治疗前均显著升高,PEF较治疗前均显著增快,且治疗组优于对照组,差异有统计学意义(P<0.05);两组患者在治疗期间的不良反应发生率方面,差异无统计学意义(P>0.05)。结论对于处于急性发作期慢阻肺患者,实施常规西药治疗基础上应用加味三子养亲汤治疗,可获得理想疗效,患者肺功能显著改善,气喘、咳嗽、胸闷、纳差、夜寐欠佳等中医症状显著缓解,且安全性高。Objective To investigate the clinical effects of Jiawei Sanzi Yangqin decoction in the treatment of chronic obstructive pulmonary disease during acute exacerbation.Methods From January 2020 to January 2022 seventy-eight patients with chronic obstructive pulmonary disease in acute exacerbation admitted to the Department of Traditional Chinese Medicine of Suqian Hospital of Nanjing Gulou Hospital Group were conveniently selected as the subjects of this study and divided into treatment group(39 cases)and control group(39 cases)by random number table method.The control group was treated with conventional western medicine,and the treatment group was treated with a combination of Chinese medicine Jiawei Sanzi Yangqin decoction on the basis.The treatment effect,TCM symptoms,improvement of lung function and adverse drug reactions were analyzed.Results The total effective rate of the treatment group(92.31%)was higher than that of the control group,and the difference was statistically significant(χ^(2)=4.523,P<0.05).After treatment,the TCM syndrome scores(asthma,chest tightness,cough,and expectoration)in the two groups were reduced,and the scores of asthma(1.09±0.03)points,chest tightness scores(1.23±0.14)points,cough scores(1.45±0.10)points,and expectoration scores(1.12±0.13)points in the treatment group were lower than those in the control group,and the difference was statistically significant(t=58.566,28.986,29.747,29.092,P<0.05).After treatment,FVC and FEV1 in both groups significantly increased compared to before treatment,while PEF significantly increased faster than before treatment,and the treatment group were better than those in the control group,the difference was statistically significant(P<0.05).There was no statistically significant difference in the incidence of adverse reactions between the two groups of patients during treatment(P>0.05).Conclusion In patients with chronic obstructive pulmonary disease in the acute exacerbation phase,the implementation of conventional Western medicine treatment based o

关 键 词：急性发作期慢阻肺 加味三子养亲汤 中医症状 

分 类 号：R28[医药卫生—中药学]