全膝关节表面置换术治疗晚期骨关节炎的效果分析  

Analysis of the Effect of Total Knee Surface Replacement for Advanced Osteoarthritis

作　　者：顾署光 GU Shuguang(Department of Orthopedics,Xuzhou Mining Hospital,Xuzhou,Jiangsu Province,221000 China)

机构地区：[1]徐州市矿山医院骨科,江苏徐州221000

出　　处：《中外医疗》2023年第18期102-106,共5页China & Foreign Medical Treatment

摘　　要：目的分析予以晚期骨关节炎患者全膝关节表面置换术治疗的临床效果。方法方便选择2020年1月—2022年12月间徐州市矿山医院接收的56例晚期骨关节炎患者为研究对象,以随机数表法均分为两组,接受关节镜下膝关节清除术治疗的28例为对照组,接受全膝关节表面置换术治疗的28例为观察组。对比两组治疗效果、膝关节功能、骨代谢指标及并发症。结果观察组治疗有效率为92.86%,高于对照组的71.43%,差异有统计学意义(χ^(2)=4.383,P<0.05)。两组术前HSS、WOMAC评分比较,差异无统计学意义(P>0.05);术后,观察组HSS评分较对照组更高,WOMAC评分较对照组更低,差异有统计学意义(P<0.05)。两组术前OPG、BALP、BGP水平比较,差异无统计学意义(P>0.05);术后,观察组OPG、BALP、BGP水平分别为(227.23±19.43)pg/mL、(53.16±5.71)U/L、(7.24±1.24)g/L,均高于对照组的(163.25±18.57)pg/mL、(45.26±6.12)U/L、(6.02±1.02)g/L,差异有统计学意义(t=12.596、4.994、4.021,P<0.05)。两组并发症发生率分别为7.14%、17.86%,差异无统计学意义(χ^(2)=0.653,P>0.05)。结论晚期骨关节炎患者应用全膝关节表面置换术治疗,效果确切,使其膝关节功能及其骨代谢指标得到改善,减少手术并发症。Objective To analyze the clinical effect of total knee surface arthroplasty treatment for patients with advanced osteoarthritis.Methods From January 2020 to December 2022,56 patients with advanced osteoarthritis received by Xuzhou Mine Hospital were conveniently selected as the research objects.They were equally divided into two groups by random number table method.28 patients who received knee joint clearance under arthroscopy were the control group,and 28 patients who received total knee joint surface replacement were the observation group.Compared the treatment effects,knee joint function,bone metabolism indicators,and complications between the two groups.Results The effective rate of treatment in the observation group was 92.86%,which was higher than 71.43%in the control group,and the difference was statistically significant(χ^(2)=4.383,P<0.05).There was no statistically significant difference in preoperative HSS and WOMAC scores between the two groups(P>0.05);after surgery,the HSS score of the observation group was higher than that of the control group,and the WOMAC score was lower than that of the control group,and the difference was statistically significant(P<0.05).There was no statistically significant difference in preoperative OPG,BALP,and BGP levels between the two groups(P>0.05);after surgery,the levels of OPG,BALP,and BGP in the observation group were(227.23±19.43)pg/mL,(53.16±5.71)U/L,and(7.24±1.24)g/L,respectively,which were higher than those in the control group(163.25±18.57)pg/mL,(45.26±6.12)U/L,and(6.02±1.02)g/L,and the difference was statistically significant(t=12.596,4.994,4.021,P<0.05).The incidence of complications in the two groups was 7.14%and 17.86%,respectively,and the difference was not statistically significant(χ^(2)=0.653,P>0.05).Conclusion The application of total knee surface replacement for patients with advanced osteoarthritis was effective,resulting in improvement of their knee function and their bone metabolic indexes and reduction of surgical complications.

关 键 词：晚期骨关节炎 全膝关节表面置换术 并发症 膝关节功能 骨代谢指标 

分 类 号：R684[医药卫生—骨科学]