“三位一体”骨修复策略在骨质疏松性骨折治疗中的应用  

Application of the"three‑in‑one"bone repair strategy in the treatment of osteoporotic fractures

作　　者：陈晓 胡衍[1,2] 苏佳灿 Chen Xiao;Hu Yan;Su Jiacan(Department of Orthopedics,Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine,Shanghai 200096,China;Shanghai University Institute of Translational Medicine,Shanghai 200444,China)

机构地区：[1]上海交通大学医学院附属新华医院骨科,上海200096 [2]上海大学转化医学研究院,上海200444

出　　处：《中华创伤杂志》2023年第6期494-499,共6页Chinese Journal of Trauma

基　　金：国家自然科学基金(92249303,82230071)。

摘　　要：骨质疏松性骨折继发于骨质疏松症,其发病率快速升高,是老年人群致残、致死的重要原因,目前在围术期管理、手术技术和术后康复方面缺少规范指导,导致并发症多、治疗效果差。笔者前期提出“三位一体”骨修复策略,即积极抗骨质疏松、合理骨植入和加速骨愈合。现针对骨质疏松性骨折手术治疗过程中的围术期管理、手术注意事项和术后防治二次骨折等核心环节,进一步阐述“三位一体”骨修复策略的具体应用,提倡围术期积极抗骨质疏松治疗和早期康复训练、规范手术内固定选择和植骨方法、防治二次骨折并发症,推进骨质疏松性骨折的规范化治疗,以改善患者预后。Osteoporotic fractures secondary to osteoporosis increase very rapidly in incidence,and have become a major cause of disability and mortality in the elderly population.Currently,there have no standard guidelines for perioperative management,surgery and postoperative rehabilitation,causing multiple complications and poor therapeutic outcome.The authors previously proposed bone repair strategies including active anti-osteoporosis,adequate bone grafting and bone healing acceleration,namely"three-in-one"bone repair strategy.The care steps in osteoporotic fracture surgery inluded perioperative management,operative precaution,and postoperative prevention of secondary fractures.With this in mind,the authors further discussed the detailed application of"three-in-one"bone repair strategy including perioperative active anti-osteoporosis treatment,early rehabilitation training,standardized internal fixation selection,standard bone grafting methods and prevention of secondary complications,so as to promote the standardized treatment of osteoporotic fractures and improve the prognosis.

关 键 词：骨质疏松性骨折 骨质吸收 骨代用品 康复 

分 类 号：R687.3[医药卫生—骨科学]